List of publications

DokumenttypErscheinungsjahrTitelAutorenHerausgeber
article2023Neutralizing the Impact of the Virulence Factor LecA from Pseudomonas aeruginosa on Human Cells with New Glycomimetic InhibitorsZahorska, Eva; Rosato, Francesca; Stober, Kai; Kuhaudomlarp, Sakonwan; Meiers, Joscha; Hauck, Dirk; Reith, Dorina; Gillon, Emilie; Rox, Katharina; Imberty, Anne; Römer, Winfried; Titz, Alexander
article2023Glycomimetics for the inhibition and modulation of lectinsLeusmann, Steffen; Ménová, Petra; Shanin, Elena; Titz, Alexander; Rademacher, Christoph
article2022Nano-in-Microparticles for Aerosol Delivery of Antibiotic-Loaded, Fucose-Derivatized, and Macrophage-Targeted Liposomes to Combat Mycobacterial Infections: In Vitro Deposition, Pulmonary Barrier Interactions, and Targeted DeliveryHuck, Benedikt C.; Thiyagarajan, Durairaj; Bali, Aghiad; Boese, Annette; Besecke, Karen F. W.; Hozsa, Constantin; Gieseler, Robert K.; Furch, Marcus; Carvalho-Wodarz, Cristiane; Waldow, Franziska; Schwudke, Dominik; Metelkina, Olga; Titz, Alexander; Huwer, Hanno; Schwarzkopf, Konrad; Hoppstädter, Jessica; Kiemer, Alexandra Kathrin; Koch, Marcus; Loretz, Brigitta; Lehr, Claus-Michael
article2022Targeting extracellular lectins of Pseudomonas aeruginosa with glycomimetic liposomesMetelkina, Olga; Huck, Benedikt; O'Connor, Jonathan S.; Koch, Marcus; Manz, Andreas; Lehr, Claus-Michael; Titz, Alexander
article2022Pineapple Lectin AcmJRL Binds SARS-CoV-2 Spike Protein in a Carbohydrate-Dependent FashionMeiers, Joscha; Dastbaz, Jan; Adam, Sebastian; Rasheed, Sari; Kirsch, Susanne H.; Meiser, Peter; Gross, Peter; Müller, Rolf; Titz, Alexander
article2022Discovery of N-β-l-Fucosyl Amides as High-Affinity Ligands for the Pseudomonas aeruginosa Lectin LecBMała, Patrycja; Siebs, Eike; Meiers, Joscha; Rox, Katharina; Varrot, Annabelle; Imberty, Anne; Titz, Alexander
article2022Targeting undruggable carbohydrate recognition sites through focused fragment library designShanina, Elena; Kuhaudomlarp, Sakonwan; Siebs, Eike; Fuchsberger, Felix F.; Denis, Maxime; da Silva Figueiredo Celestino Gomes, Priscila; Clausen, Mads H.; Seeberger, Peter H.; Rognan, Didier; Titz, Alexander; Imberty, Anne; Rademacher, Christoph
article2022β-Boronic Acid-Substituted Bodipy Dyes for Fluorescence Anisotropy Analysis of Carbohydrate BindingHoffmann, Caroline; Jourdain, Matthias; Grandjean, Alexander; Titz, Alexander; Jung, Gregor
article2022NamZ1 and NamZ2 from the Oral Pathogen Tannerella forsythia Are Peptidoglycan Processing Exo-β-N-Acetylmuramidases with Distinct Substrate SpecificitiesBorisova, Marina; Balbuchta, Katja; Lovering, Andrew; Titz, Alexander; Mayer, Christoph
article2022Lectin-Targeted Prodrugs Activated by Pseudomonas aeruginosa for Self-Destructive Antibiotic ReleaseMeiers, Joscha; Rox, Katharina; Titz, Alexander
article2021Targeting the Central Pocket of the Pseudomonas aeruginosa Lectin LecASiebs, Eike; Shanina, Elena; Kuhaudomlarp, Sakonwan; da Silva Figueiredo Celestino Gomes, Priscila; Fortin, Cloé; Seeberger, Peter H.; Rognan, Didier; Rademacher, Christoph; Imberty, Anne; Titz, Alexander
article2021Short Peptides and Their Mimetics as Potent Antibacterial Agents and Antibiotic AdjuvantsPanjla, Apurva; Kaul, Grace; Chopra, Sidharth; Titz, Alexander; Verma, Sandeep
article2021The exo-β-N-acetylmuramidase NamZ from Bacillus subtilis is the founding member of a family of exo-lytic peptidoglycan hexosaminidasesMüller, Maraike; Calvert, Matthew; Hottmann, Isabel; Kluj, Robert Maria; Teufel, Tim; Balbuchta, Katja; Engelbrecht, Alicia; Selim, Khaled A.; Xu, Qingping; Borisova, Marina; Titz, Alexander; Mayer, Christoph
article2021Towards the sustainable discovery and development of new antibioticsMiethke, Marcus; Pieroni, Marco; Weber, Tilmann; Brönstrup, Mark; Hammann, Peter; Halby, Ludovic; Arimondo, Paola B.; Glaser, Philippe; Aigle, Bertrand; Bode, Helge B.; Moreira, Rui; Li, Yanyan; Luzhetskyy, Andriy; Medema, Marnix H.; Pernodet, Jean-Luc; Stadler, Marc; Tormo, José Rubén; Genilloud, Olga; Truman, Andrew W.; Weissman, Kira J.; Takano, Eriko; Sabatini, Stefano; Stegmann, Evi; Brötz-Oesterhelt, Heike; Wohlleben, Wolfgang; Seemann, Myriam; Empting, Martin; Hirsch, Anna K. H.; Loretz, Brigitta; Lehr, Claus-Michael; Titz, Alexander; Herrmann, Jennifer; Jaeger, Timo; Alt, Silke; Hesterkamp, Thomas; Winterhalter, Mathias; Schiefer, Andrea; Pfarr, Kenneth; Hoerauf, Achim; Graz, Heather; Graz, Michael; Lindvall, Mika; Ramurthy, Savithri; Karlén, Anders; van Dongen, Maarten; Petkovic, Hrvoje; Keller, Andreas; Peyrane, Frédéric; Donadio, Stefano; Fraisse, Laurent; Piddock, Laura J. V.; Gilbert, Ian H.; Moser, Heinz E.; Müller, Rolf
article2020A rapid synthesis of low-nanomolar divalent LecA inhibitors in four linear steps from d-galactose pentaacetateZahorska, Eva; Kuhaudomlarp, Sakonwan; Minervini, Saverio; Yousaf, Sultaan; Lepsik, Martin; Kinsinger, Thorsten; Hirsch, Anna K. H.; Imberty, Anne; Titz, Alexander
article2020Protein-observed 19F NMR of LecA from Pseudomonas aeruginosaShanina, Elena; Siebs, Eike; Zhang, Hengxi; Varón Silva, Daniel; Joachim, Ines; Titz, Alexander; Rademacher, Christoph
article2020Directing Drugs to Bugs: Antibiotic-Carbohydrate Conjugates Targeting Biofilm-Associated Lectins of Pseudomonas aeruginosaMeiers, Joscha; Zahorska, Eva; Röhrig, Teresa; Hauck, Dirk; Wagner, Stefanie; Titz, Alexander
article2020Non-Carbohydrate Glycomimetics as Inhibitors of Calcium(II)-Binding LectinsKuhaudomlarp, Sakonwan; Siebs, Eike; Shanina, Elena; Topin, Jérémie; Joachim, Ines; da Silva Figueiredo Celestino Gomes, Priscila; Varrot, Annabelle; Rognan, Didier; Rademacher, Christoph; Imberty, Anne; Titz, Alexander
article2019Lectin antagonists in infection, immunity, and inflammationMeiers, Joscha; Siebs, Eike; Zahorska, Eva; Titz, Alexander
article2019Chemical synthesis of tripeptide thioesters for the biotechnological incorporation into the myxobacterial secondary metabolite argyrin via mutasynthesisSiebert, David C. B.; Sommer, Roman; Pogorevc, Domen; Hoffmann, Michael; Wenzel, Silke C.; Müller, Rolf; Titz, Alexander
article2019Anti-biofilm Agents against Pseudomonas aeruginosa : A Structure-Activity Relationship Study of C-Glycosidic LecB InhibitorsSommer, Roman; Rox, Katharina; Wagner, Stefanie; Hauck, Dirk; Henrikus, Sarah S.; Newsad, Shelby; Arnold, Tatjana; Ryckmans, Thomas; Brönstrup, Mark; Imberty, Anne; Varrot, Annabelle; Hartmann, Rolf W.; Titz, Alexander
article2019Induction of rare conformation of oligosaccharide by binding to calcium-dependent bacterial lectin : X-ray crystallography and modelling studyLepsik, Martin; Sommer, Roman; Kuhaudomlarp, Sakonwan; Lelimousin, Mickaël; Paci, Emanuele; Varrot, Annabelle; Titz, Alexander; Imberty, Anne
article2018Pathoblockers or antivirulence drugs as a new option for the treatment of bacterial infectionsCalvert, Matthew B.; Jumde, Varsha R.; Titz, Alexander
article2018Virtual Screening Against Carbohydrate-Binding Proteins : Evaluation and Application to Bacterial Burkholderia ambifaria LectinDingjan, Tamir; Gillon, Émilie; Imberty, Anne; Pérez, Serge; Titz, Alexander; Ramsland, Paul A.; Yuriev, Elizabeth
article2018N-Acetylmuramic Acid (MurNAc) Auxotrophy of the Oral Pathogen Tannerella forsythia: Characterization of a MurNAc Kinase and Analysis of Its Role in Cell Wall MetabolismHottmann, Isabel; Mayer, Valentina M. T.; Tomek, Markus B.; Friedrich, Valentin; Calvert, Matthew B.; Titz, Alexander; Schäffer, Christina; Mayer, Christoph
article2017Ciprofloxacin-loaded lipid-core nanocapsules as mucus penetrating drug delivery system intended for the treatment of bacterial infections in cystic fibrosisTorge, Afra; Wagner, Stefanie; Chaves, Paula S.; Oliveira, Edilene G.; Guterres, Silvia S.; Pohlmann, Adriana R.; Titz, Alexander; Schneider, Marc; Beck, Ruy C. R.
article2017Glycomimetic, Orally Bioavailable LecB Inhibitors Block Biofilm Formation of Pseudomonas aeruginosaSommer, Roman; Wagner, Stefanie; Rox, Katharina; Varrot, Annabelle; Hauck, Dirk; Wamhoff, Eike-Christian; Schreiber, Janine; Ryckmans, Thomas; Brunner, Thomas; Rademacher, Christoph; Hartmann, Rolf W.; Brönstrup, Mark; Imberty, Anne; Titz, Alexander
article2017Photorhabdus luminescens lectin A (PllA) : A new probe for detecting α-galactoside-terminating glycoconjugatesBeshr, Ghamdan; Sikandar, Asfandyar; Jemiller, Eva-Maria; Klymiuk, Nikolai; Hauck, Dirk; Wagner, Stefanie; Wolf, Eckhard; Koehnke, Jesko; Titz, Alexander
article2017An efficient synthesis of 1,6-anhydro-N-acetylmuramic acid from N-acetylglucosamineCalvert, Matthew B.; Mayer, Christoph; Titz, Alexander
Welcome
ORCID: iD icon https://orcid.org/0000-0001-7408-5084
Name:Titz, Alexander
Faculty: NT - Naturwissenschaftlich- Technische Fakultät
Department: NT - Chemie
Professorship:NT - Univ.-Prof. Dr. phil. Alexander Titz
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