List of publications

DokumenttypErscheinungsjahrTitelAutorenHerausgeber
article2024Genetically Engineered Filamentous Bacteriophages Displaying TGF-β1 Promote Angiogenesis in 3D MicroenvironmentsBaek, In-Hyuk; Helms, Volkhard; Kim, Youngjun
Other2024Engineering Material Properties of Transcription Factor Condensates to Control Gene Expression in Mammalian Cells and MiceFischer, Alexandra A.M.; Robertson, Hanah B.; Kong, Deqiang; Grimm, Merlin M.; Grether, Jakob; Groth, Johanna; Baltes, Carsten; Fliegauf, Manfred; Lautenschläger, Franziska; Grimbacher, Bodo; Ye, Haifeng; Helms, Volkhard; Weber, Winfried
article2024Engineering Material Properties of Transcription Factor Condensates to Control Gene Expression in Mammalian Cells and MiceFischer, Alexandra A.M.; Robertson, Hanah B.; Kong, Deqiang; Grimm, Merlin M.; Grether, Jakob; Groth, Johanna; Baltes, Carsten; Fliegauf, Manfred; Lautenschläger, Franziska; Grimbacher, Bodo; Ye, Haifeng; Helms, Volkhard; Weber, Wilfried
article2023The ER Protein Translocation Channel Subunit Sbh1 Controls Virulence of Cryptococcus neoformansSantiago-Tirado, Felipe H.; Hurtaux, Thomas; Geddes-McAlister, Jennifer; Nguyen, Duy; Helms, Volkhard; Doering, Tamara L.; Römisch, Karin
article2023Identification of molecular candidates which regulate calcium-dependent CD8+ T-cell cytotoxicityZöphel, Sylvia; Schäfer, Gertrud; Nazarieh, Maryam; Konetzki, Verena; Hoxha, Cora; Meese, Eckart; Hoth, Markus; Helms, Volkhard; Hamed, Mohamed; Schwarz, Eva C.
article2023Sec61 channel subunit Sbh1/Sec61β promotes ER translocation of proteins with suboptimal targeting sequences and is fine-tuned by phosphorylationBarbieri, Guido; Simon, Julien; Lupusella, Cristina R.; Pereira, Fabio; Elia, Francesco; Meyer, Hadar; Schuldiner, Maya; Hanes, Steven D.; Nguyen, Duy; Helms, Volkhard; Römisch, Karin
article2023Differential exon usage of developmental genes is associated with deregulated epigenetic marksDo, Hoang Thu Trang; Shanak, Siba; Barghash, Ahmad; Helms, Volkhard
article2022Optimized Data Set and Feature Construction for Substrate Prediction of Membrane TransportersDenger, Andreas; Helms, Volkhard
article2022How Peptides Bind to PSD-95/Discs-Large/ZO-1 DomainsKünzel, Nicolas; Helms, Volkhard
article2022How phosphorylation of peptides affects their interaction with 14-3-3η domainsKünzel, Nicolas; Helms, Volkhard
Other2022The ER protein translocation channel subunit Sbh1 controls virulence of Cryptococcus neoformansSantiago-Tirado, Felipe H.; Hurtaux, Thomas; Geddes-McAlister, Jennifer; Nguyen, Duy; Helms, Volkhard; Doering, Tamara L.; Römisch, Karin
article2022Unspecific CTL Killing Is Enhanced by High Glucose via TNF-Related Apoptosis-Inducing LigandYang, Wenjuan; Denger, Andreas; Diener, Caroline Elisabeth; Küppers, Frederic; Soriano-Baguet, Leticia; Schäfer, Gertrud; Yanamandra, Archana K.; Zhao, Renping; Knörck, Arne; Schwarz, Eva C.; Hart, Martin; Lammert, Frank; Roma, Leticia Prates; Brenner, Dirk; Christidis, Grigorios; Helms, Volkhard; Meese, Eckart; Hoth, Markus; Qu, Bin
article2022PEX19 Coordinates Neutral Lipid Storage in Cells in a Peroxisome-Independent FashionLyschik, Sven; Lauer, Anna A.; Roth, Tanja; Janitschke, Daniel; Hollander, Markus; Will, Thorsten; Hartmann, Tobias; Kopito, Ron R.; Helms, Volkhard; Grimm, Marcus O. W.; Schrul, Bianca
article2022Synthesis, Biological Evaluation and Docking Studies of Ring-Opened Analogues of Ipomoeassin FO’Keefe, Sarah; Bhadra, Pratiti; Duah, Kwabena B.; Zong, Guanghui; Tenay, Levise; Andrews, Lauren; Schneider, Hayden; Anderson, Ashley; Hu, Zhijian; Aljewari, Hazim S.; Hall, Belinda S.; Simmonds, Rachel E.; Helms, Volkhard; High, Stephen; Shi, Wei Q.
article2022Proteomics Identifies Substrates and a Novel Component in hSnd2-Dependent ER Protein TargetingTirincsi, Andrea; O’Keefe, Sarah; Nguyen, Duy; Sicking, Mark; Dudek, Johanna; Förster, Friedrich; Jung, Martin; Hadzibeganovic, Drazena; Helms, Volkhard; High, Stephen; Zimmermann, Richard; Lang, Sven
article2022Is the proteomic composition of the salivary pellicle dependent on the substrate material?Trautmann, Simone; Künzel, Nicolas; Fecher-Trost, Claudia; Barghash, Ahmad; Dudek, Johanna; Flockerzi, Veit; Helms, Volkhard; Hannig, Matthias
article2021Dysregulation of cholesterol homeostasis in human lung cancer tissue and tumour-associated macrophagesHoppstädter, Jessica; Dembek, Anna; Höring, Marcus; Schymik, Hanna S.; Dahlem, Charlotte; Sultan, Afnan; Wirth, Natalie; Al-Fityan, Salma; Diesel, Britta; Gasparoni, Gilles; Walter, Jörn; Helms, Volkhard; Huwer, Hanno; Simon, Martin; Liebisch, Gerhard; Schulz, Marcel H.; Kiemer, Alexandra K.
article2021A Methylation-Directed, Synthetic Pap Switch Based on Self-Complementary Regulatory DNA Reconstituted in an All E. coli Cell-Free Expression SystemWorst, Emanuel G.; Finkler, Marc; Schenkelberger, Marc; Kurt, Ömer; Helms, Volkhard; Noireaux, Vincent; Ott, Albrecht
article2021A longer isoform of Stim1 is a negative SOCE regulator but increases cAMP-modulated NFAT signalingKnapp, Mona L.; Alansary, Dalia; Poth, Vanessa; Förderer, Kathrin; Sommer, Frederik; Zimmer, David; Schwarz, Yvonne; Künzel, Nicolas; Kless, Achim; Machaca, Khaled; Helms, Volkhard; Mühlhaus, Timo; Schroda, Michael; Lis, Annette; Niemeyer, Barbara A.
article2021ProPores2: Web Service and Stand-Alone Tool for Identifying, Manipulating, and Visualizing Pores in Protein StructuresHollander, Markus; Rasp, David; Aziz, Moomal; Helms, Volkhard
article2021Quantitative Proteomics and Differential Protein Abundance Analysis after Depletion of Putative mRNA Receptors in the ER Membrane of Human Cells Identifies Novel Aspects of mRNA Targeting to the ERBhadra, Pratiti; Schorr, Stefan; Lerner, Monika; Nguyen, Duy; Dudek, Johanna; Förster, Friedrich; Helms, Volkhard; Lang, Sven; Zimmermann, Richard
article2021Molecular Modeling of Signal Peptide Recognition by Eukaryotic Sec ComplexesBhadra, Pratiti; Helms, Volkhard
Other2021High glucose enhances antigen-independent CTL killing via TRAILYang, Wenjuan; Denger, Andreas; Diener, Caroline; Küppers, Frederic; Soriano-Baguet, Leticia; Schäfer, Gertrud; Yanamandra, Archana K.; Zhao, Renping; Knörck, Arne; Schwarz, Eva C.; Hart, Martin; Lammert, Frank; Roma, Leticia Prates; Brenner, Dirk; Christidis, Grigorios; Helms, Volkhard; Meese, Eckart; Hoth, Markus; Qu, Bin
article2021Quantitative Proteomics and Differential Protein Abundance Analysis after the Depletion of PEX3 from Human Cells Identifies Additional Aspects of Protein Targeting to the ERZimmermann, Richard; Lang, Sven; Lerner, Monika; Förster, Friedrich; Nguyen, Duy; Helms, Volkhard; Schrul, Bianca
article2021How does Sec63 affect the conformation of Sec61 in yeast?Bhadra, Pratiti; Yadhanapudi, Lalitha; Römisch, Karin; Helms, Volkhard
article2021Identification of Biomarkers Controlling Cell Fate In Blood Cell DevelopmentNazarieh, Maryam; Hoeppner, Marc; Helms, Volkhard
article2020Identification of signal peptide features for substrate specificity in human Sec62/Sec63-dependent ER protein importSchorr, Stefan; Nguyen, Duy; Haßdenteufel, Sarah; Nagaraj, Nagarjuna; Cavalié, Adolfo; Greiner, Markus; Weissgerber, Petra; Loi, Marisa; Paton, Adrienne W; Paton, James C; Molinari, Maurizio; Förster, Friedrich; Dudek, Johanna; Lang, Sven; Helms, Volkhard; Zimmermann, Richard
article2020TRAM1 protein may support ER protein import by modulating the phospholipid bilayer near the lateral gate of the Sec61-channelKlein, Marie-Christine; Lerner, Monika; Nguyen, Duy; Pfeffer, Stefan; Dudek, Johanna; Förster, Friedrich; Helms, Volkhard; Lang, Sven; Zimmermann, Richard
article2020Interorganelle Tethering to Endocytic Organelles Determines Directional Cytokine Transport in CD4+ T CellsZhou, Yan; Zhao, Renping; Schwarz, Eva C.; Akbar, Rahmad; Kaba, Mayis; Pattu, Varsha; Helms, Volkhard; Rieger, Heiko; Nunes-Hasler, Paula; Qu, Bin
article2020Deep Proteomic Insights into the Individual Short-Term Pellicle Formation on Enamel-An In Situ Pilot StudyTrautmann, Simone; Künzel, Nicolas; Fecher-Trost, Claudia; Barghash, Ahmad; Schalkowsky, Pascal; Dudek, Johanna; Delius, Judith; Helms, Volkhard; Hannig, Matthias
article2020DNA methylation and the core pluripotency networkShanak, Siba; Helms, Volkhard
article2020Analysis of the dynamics of Staphylococcus aureus binding to white blood cells using whole blood assay and geno-to-pheno mappingGaidar, Daria; Jonas, Alice; Akulenko, Ruslan; Ruffing, Ulla; Herrmann, Mathias; Helms, Volkhard; von Müller, Lutz
article2019Differential analysis of combinatorial protein complexes with CompleXChangeWill, Thorsten; Helms, Volkhard
article2019Redox signals at the ER-mitochondria interface control melanoma progressionZhang, Xin; Gibhardt, Christine S.; Will, Thorsten; Stanisz, Hedwig; Körbel, Christina; Mitkovski, Miso; Stejerean, Ioana; Cappello, Sabrina; Pacheu-Grau, David; Dudek, Jan; Tahbaz, Nasser; Mina, Lucas; Simmen, Thomas; Laschke, Matthias W.; Menger, Michael D.; Schön, Michael P.; Helms, Volkhard; Niemeyer, Barbara A.; Rehling, Peter; Vultur, Adina; Bogeski, Ivan
article2019Relative Principal Components Analysis: Application to Analyzing Biomolecular Conformational ChangesAhmad, Mazen; Helms, Volkhard; Kalinina, Olga V.; Lengauer, Thomas
article2019Eeyarestatin Compounds Selectively Enhance Sec61-Mediated Ca2+ Leakage from the Endoplasmic ReticulumGamayun, Igor; O'Keefe, Sarah; Pick, Tillman; Klein, Marie-Christine; Nguyen, Duy; McKibbin, Craig; Piacenti, Michela; Williams, Helen M.; Flitsch, Sabine L.; Whitehead, Roger C.; Swanton, Eileithyia; Helms, Volkhard; High, Stephen; Zimmermann, Richard; Cavalié, Adolfo
article2019The mRNA-binding Protein TTP/ZFP36 in Hepatocarcinogenesis and Hepatocellular CarcinomaKröhler, Tarek; Kessler, Sonja M.; Hosseini, Kevan; List, Markus; Barghash, Ahmad; Patial, Sonika; Laggai, Stephan; Gemperlein, Katja; Haybaeck, Johannes; Müller, Rolf; Helms, Volkhard; Schulz, Marcel H.; Hoppstädter, Jessica; Blackshear, Perry J.; Kiemer, Alexandra K.
article2019SNP and indel frequencies at transcription start sites and at canonical and alternative translation initiation sites in the human genomeNeininger, Kerstin; Marschall, Tobias; Helms, Volkhard
article2019IGF2 mRNA Binding Protein 2 Transgenic Mice Are More Prone to Develop a Ductular Reaction and to Progress Toward CirrhosisCzepukojc, Beate; Abuhaliema, Ali; Barghash, Ahmad; Tierling, Sascha; Naß, Norbert; Simon, Yvette; Körbel, Christina; Cadenas, Cristina; van Hul, Noemi; Sachinidis, Agapios; Hengstler, Jan G; Helms, Volkhard; Laschke, Matthias W.; Walter, Jörn; Haybaeck, Johannes; Leclercq, Isabelle; Kiemer, Alexandra; Kessler, Sonja M.
article2019Topology Consistency of Disease-specific Differential Co-regulatory NetworksNazarieh, Maryam; Rajula, Hema Sekhar Reddy; Helms, Volkhard
article2019ER import of small human presecretory proteins: components and mechanismsHaßdenteufel, Sarah; Nguyen, Duy; Helms, Volkhard; Lang, Sven; Zimmermann, Richard
article2018AXER is an ATP/ADP exchanger in the membrane of the endoplasmic reticulumKlein, Marie-Christine; Zimmermann, Katharina; Schorr, Stefan; Landini, Martina; Klemens, Patrick A. W.; Altensell, Jacqueline; Jung, Martin; Krause, Elmar; Nguyen, Duy; Helms, Volkhard; Rettig, Jens; Fecher-Trost, Claudia; Cavalié, Adolfo; Hoth, Markus; Bogeski, Ivan; Neuhaus, H Ekkehard; Zimmermann, Richard; Lang, Sven; Haferkamp, Ilka
article2018Adding phosphorylation events to the core oscillator driving the cell cycle of fission yeastHumaidan, Dania; Breinig, Frank; Helms, Volkhard
article2018Copy Number Alterations in Tumor Genomes Deleting Antineoplastic Drug Targets Partially Compensated by Complementary AmplificationsTran, Ha Vu; Kiemer, Alexandra; Helms, Volkhard
article2018Identification of novel diabetes impaired miRNA-transcription factor co-regulatory networks in bone marrow-derived Lin-/VEGF-R2+ endothelial progenitor cellsIrhimeh, Mohammad R.; Hamed, Mohamed; Barthelmes, Daniel; Gladbach, Yvonne; Helms, Volkhard; Shen, Weiyong; Gillies, Mark C.
article2018Proteomic Analysis of the Initial Oral Pellicle in Caries-Active and Caries-Free IndividualsTrautmann, Simone; Barghash, Ahmad; Fecher-Trost, Claudia; Schalkowsky, Pascal; Hannig, Christian; Kirsch, Jasmin; Rupf, Stefan; Keller, Andreas; Helms, Volkhard; Hannig, Matthias
article2018Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein importNguyen, Duy; Stutz, Regine; Schorr, Stefan; Lang, Sven; Pfeffer, Stefan; Freeze, Hudson H.; Förster, Friedrich; Helms, Volkhard; Dudek, Johanna; Zimmermann, Richard
article2018Prediction of Synergistic Toxicity of Binary Mixtures to Vibrio fischeri Based on Biomolecular Interaction NetworksKim, Jongwoon; Fischer, Max; Helms, Volkhard
article2018ALLO: A tool to discriminate and prioritize allosteric pocketsAkbar, Rahmad; Helms, Volkhard
article2018MutaNET: a tool for automated analysis of genomic mutations in gene regulatory networksHollander, Markus; Hamed, Mohamed; Helms, Volkhard; Neininger, Kerstin
article2017An Update on Sec61 Channel Functions, Mechanisms, and Related DiseasesLang, Sven; Pfeffer, Stefan; Lee, Po-Hsien; Cavalié, Adolfo; Helms, Volkhard; Förster, Friedrich; Zimmermann, Richard
article2017Randomization Strategies Affect Motif Significance Analysis in TF-miRNA-Gene Regulatory NetworksSadegh, Sepideh; Nazarieh, Maryam; Spaniol, Christian; Helms, Volkhard
article2017The long non-coding RNA H19 suppresses carcinogenesis and chemoresistance in hepatocellular carcinomaSchultheiss, Christina S.; Laggai, Stephan; Czepukojc, Beate; Hussein, Usama K.; List, Markus; Barghash, Ahmad; Tierling, Sascha; Hosseini, Kevan; Golob-Schwarzl, Nicole; Pokorny, Juliane; Hachenthal, Nina; Schulz, Marcel; Helms, Volkhard; Walter, Jörn Erik; Zimmer, Vincent; Lammert, Frank; Bohle, Rainer M.; Dandolo, Luisa; Haybaeck, Johannes; Kiemer, Alexandra; Kessler, Sonja M.
article2017Human profilin 1 is a negative regulator of CTL mediated cell-killing and migrationSchoppmeyer, Rouven; Zhao, Renping; Cheng, He; Hamed, Mohamed; Liu, Chen; Zhou, Xiao; Schwarz, Eva C.; Zhou, Yan; Knörck, Arne; Schwär, Gertrud; Ji, Shunrong; Liu, Liang; Long, Jiang; Helms, Volkhard; Hoth, Markus; Yu, Xianjun; Qu, Bin
article2017Methylation-targeted specificity of the DNA binding proteins R.DpnI and MeCP2 studied by molecular dynamics simulationsShanak, Siba; Ulucan, Ozlem; Helms, Volkhard
article2017Rewiring of the inferred protein interactome during blood development studied with the tool PPICompareWill, Thorsten; Helms, Volkhard
article2017Bystander cells enhance NK cytotoxic efficiency by reducing search timeZhou, Xiao; Zhao, Renping; Schwarz, Karsten; Mangeat, Matthieu; Schwarz, Eva C.; Hamed, Mohamed; Bogeski, Ivan; Helms, Volkhard; Rieger, Heiko; Qu, Bin
article2017Community-Associated Staphylococcus aureus from Sub-Saharan Africa and Germany: A Cross-Sectional Geographic Correlation StudyRuffing, Ulla; Alabi, Abraham; Kazimoto, Theckla; Vubil, Delfino C.; Akulenko, Ruslan; Abdulla, Salim; Alonso, Pedro; Bischoff, Markus; Germann, Anja; Grobusch, Martin P.; Helms, Volkhard; Hoffmann, Jonas; Kern, Winfried V.; Kremsner, Peter G.; Mandomando, Inacio; Mellmann, Alexander; Peters, Georg; Schaumburg, Frieder; Schubert, Sabine; Strauß, Lena; Tanner, Marcel; Briesen, Hagen von; Wende, Laura; Müller, Lutz von; Herrmann, Mathias
article2017Expression regulation by a methyl-CpG binding domain in an E. coli based, cell-free TX-TL systemSchenkelberger, Marc; Shanak, Siba; Finkler, Mark R.; Worst, Emanuel G.; Noireaux, Vincent; Helms, Volkhard; Ott, Alina
article2017Elucidating the energetic contributions to the binding free energyAhmad, Mazen; Helms, Volkhard; Kalinina, Olga V.; Lengauer, Thomas
article2017Linking Hematopoietic Differentiation to Co-Expressed Sets of Pluripotency-Associated and Imprinted Genes and to Regulatory microRNA-Transcription Factor MotifsHamed, Mohamed; Trumm, Johannes; Spaniol, Christian; Sethi, Riccha; Irhimeh, Mohammad R.; Fuellen, Georg; Paulsen, Martina; Helms, Volkhard
Welcome
ORCID: iD icon https://orcid.org/0000-0002-2180-9154
Name:Helms, Volkhard
Faculty: NT - Naturwissenschaftlich- Technische Fakultät
Department: NT - Biowissenschaften
Professorship:NT - Prof. Dr. Volkhard Helms
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