List of publications

DokumenttypErscheinungsjahrTitelAutorenHerausgeber
article2022Reviewing toxicokinetics with a focus on metabolism of new psychoactive substances in the zebrafish (larvae) modelWagmann, Lea; Meyer, Markus R.
article2022In vitro metabolic fate of the synthetic cannabinoid receptor agonists (quinolin-8-yl 4-methyl-3-(morpholine-4-sulfonyl)benzoate [QMMSB]) and (quinolin-8-yl 4-methyl-3-((propan-2-yl)sulfamoyl)benzoate [QMiPSB]) including isozyme mapping and carboxylesterases activity testingRichter, Matthias J.; Wagmann, Lea; Kavanagh, Pierce V.; Brandt, Simon D.; Meyer, Markus R.
article2022Induction of Liver Size Reduction in Zebrafish Larvae by the Emerging Synthetic Cannabinoid 4F-MDMB-BINACA and Its Impact on Drug MetabolismPark, Yu Mi; Dahlem, Charlotte; Meyer, Markus R.; Kiemer, Alexandra K.; Müller, Rolf; Herrmann, Jennifer
article2022Going deeper into the toxicokinetics of synthetic cannabinoids: in vitro contribution of human carboxylesterasesWagmann, Lea; Stiller, Rebecca G.; Fischmann, Svenja; Westphal, Folker; Meyer, Markus R.
article2022In Vitro and In Vivo Toxicometabolomics of the Synthetic Cathinone PCYP Studied by Means of LC-HRMS/MSHemmer, Selina; Wagmann, Lea; Pulver, Benedikt; Westphal, Folker; Meyer, Markus R.
article2022Closing the gap : development of an analytical methodology using volumetric absorptive microsampling of finger prick blood followed by LC-HRMS/MS for adherence monitoring of antihypertensive drugsJacobs, Cathy M.; Kunz, Michael; Mahfoud, Felix; Wagmann, Lea; Meyer, Markus R.
article2022Analytical toxicology of yew constituents in human blood and urine by liquid chromatography-high-resolution tandem mass spectrometryJacobs, Cathy M.; Wagmann, Lea; Meyer, Markus R.
article2021Altered metabolic pathways elucidated via untargeted in vivo toxicometabolomics in rat urine and plasma samples collected after controlled application of a human equivalent amphetamine doseHemmer, Selina; Wagmann, Lea; Meyer, Markus R.
article2021Cytotoxicity, metabolism, and isozyme mapping of the synthetic cannabinoids JWH-200, A-796260, and 5F-EMB-PINACA studied by means of in vitro systemsGampfer, Tanja M.; Wagmann, Lea; Belkacemi, Anouar; Flockerzi, Veit; Meyer, Markus R.
article2021Toxicokinetics of U-47700, tramadol, and their main metabolites in pigs following intravenous administration: is a multiple species allometric scaling approach useful for the extrapolation of toxicokinetic parameters to humans?Nordmeier, Frederike; Sihinevich, Iryna; Doerr, Adrian A.; Walle, Nadja; Laschke, Matthias W.; Lehr, Thorsten; Menger, Michael D.; Schmidt, Peter H.; Meyer, Markus R.; Schaefer, Nadine
article2021Assessing Adherence to Antihypertensive Medication by Means of Dose-Dependent Reference Plasma Concentration Ranges and Ultra-High Performance Liquid Chromatography-Ion Trap Mass Spectrometry AnalysisWagmann, Lea; Vollmer, Aline C.; Lauder, Lucas; Mahfoud, Felix; Meyer, Markus R.
article2021Development, validation, and application of a quantitative volumetric absorptive microsampling-based method in finger prick blood by means of LC-HRMS/MS applicable for adherence monitoring of antipsychoticsJacobs, Cathy M.; Wagmann, Lea; Meyer, Markus R.
article2021Recent trends in drugs of abuse metabolism studies for mass spectrometry-based analytical screening proceduresWagmann, Lea; Gampfer, Tanja M.; Meyer, Markus R.
article2021Abuse of nutmeg seeds: Detectable by means of liquid chromatography-mass spectrometry techniques?Manier, Sascha K.; Wagmann, Lea; Weber, Armin A.; Meyer, Markus R.
article2021In Vitro Metabolic Fate of the Synthetic Cannabinoid Receptor Agonists QMPSB and QMPCB (SGT-11) Including Isozyme Mapping and Esterase ActivityRichter, Matthias J.; Wagmann, Lea; Gampfer, Tanja M.; Brandt, Simon D.; Meyer, Markus R.
article2021Further development of a liquid chromatography-high-resolution mass spectrometry/mass spectrometry-based strategy for analyzing eight biomarkers in human urine indicating toxic mushroom or Ricinus communis ingestionsBambauer, Thomas P.; Wagmann, Lea; Weber, Armin A.; Meyer, Markus R.
article2021Drug adherence and psychosocial characteristics of patients presenting with hypertensive urgency at the emergency departmentLauder, Lucas; Ewen, Sebastian; Glasmacher, Julius; Lammert, Frank; Reith, Wolfgang; Schreiber, Naemi; Kaddu-Mulindwa, Dominic; Ukena, Christian; Böhm,; Meyer, Markus R.; Mahfoud, Felix
article2020Drug Administration Routes Impact the Metabolism of a Synthetic Cannabinoid in the Zebrafish Larvae ModelPark, Yu Mi; Meyer, Markus R.; Müller, Rolf; Herrmann, Jennifer
article2020How to Study the Metabolism of New Psychoactive Substances for the Purpose of Toxicological Screenings — A Follow-Up Study Comparing Pooled Human Liver S9, HepaRG Cells, and Zebrafish LarvaeWagmann, Lea; Frankenfeld, Fabian; Park, Yu Mi; Herrmann, Jennifer; Fischmann, Svenja; Westphal, Folker; Müller, Rolf; Flockerzi, Veit; Meyer, Markus R.
article2020Adherence to Antihypertensive Drugs Assessed by Hyphenated High-Resolution Mass Spectrometry Analysis of Oral FluidsLauder, Lucas; Ewen, Sebastian; Kunz, Michael; Richter, Lilian H. J.; Jacobs, Cathy M.; Kindermann, Ingrid; Böhm, Michael; Meyer, Markus R.; Mahfoud, Felix
Other2020Addendum: Hemmer, S., et al. Comparison of Three Untargeted Data Processing Workflows for Evaluating LC-HRMS Metabolomics Data. Metabolites 2020, 10, 378Hemmer, Selina; Manier, Sascha K.; Fischmann, Svenja; Westphal, Folker; Wagmann, Lea; Meyer, Markus R.
article2020Analysis of α- and β-amanitin in Human Plasma at Subnanogram per Milliliter Levels by Reversed Phase Ultra-High Performance Liquid Chromatography Coupled to Orbitrap Mass SpectrometryBambauer, Thomas P.; Wagmann, Lea; Weber, Armin A.; Meyer, Markus R.
article2020Transient Receptor Potential Vanilloid 6 (TRPV6) Proteins Control the Extracellular Matrix Structure of the Placental LabyrinthWinter, Manuel; Weissgerber, Petra; Klein, Karolin; Lux, Femke; Yildiz, Daniela; Wissenbach, Ulrich; Philipp, Stephan E.; Meyer, Markus R.; Flockerzi, Veit; Fecher-Trost, Claudia
article2020Comparison of Three Untargeted Data Processing Workflows for Evaluating LC-HRMS Metabolomics DataHemmer, Selina; Manier, Sascha K.; Fischmann, Svenja; Westphal, Folker; Wagmann, Lea; Meyer, Markus R.
article2020Liquid Chromatography-High-Resolution Mass Spectrometry-Based In Vitro Toxicometabolomics of the Synthetic Cathinones 4-MPD and 4-MEAP in Pooled Human Liver MicrosomesManier, Sascha K.; Schwermer, Florian; Wagmann, Lea; Eckstein, Niels; Meyer, Markus R.
article2020Comparison of in vitro and in vivo models for the elucidation of metabolic patterns of 7-azaindole-derived synthetic cannabinoids exemplified using cumyl-5F-P7AICAWalle, Nadja; Nordmeier, Frederike; Doerr, Adrian A.; Peters, Benjamin; Laschke, Matthias W.; Menger, Michael D.; Schmidt, Peter H.; Meyer, Markus R.; Schaefer, Nadine
article2020Altered glucocorticoid metabolism represents a feature of macroph-agingValbuena Perez, Jenny Vanessa; Linnenberger, Rebecca; Dembek, Anna; Bruscoli, Stefano; Riccardi, Carlo; Schulz, Marcel H.; Meyer, Markus R.; Kiemer, Alexandra K.; Hoppstädter, Jessica
article2020Is adipose tissue suitable for detection of (synthetic) cannabinoids? A comparative study analyzing antemortem and postmortem specimens following pulmonary administration of JWH-210, RCS-4, as well as ∆9-tetrahydrocannabinol to pigsSchaefer, Nadine; Nordmeier, Frederike; Kröll, Ann-Katrin; Körbel, Christina; Laschke, Matthias W.; Menger, Michael D.; Maurer, Hans H.; Meyer, Markus R.; Schmidt, Peter H.
article2020Impact of the used solvent on the reconstitution efficiency of evaporated biosamples for untargeted metabolomics studiesManier, Sascha K.; Meyer, Markus R.
article2020Time- and temperature-dependent postmortem concentration changes of the (synthetic) cannabinoids JWH-210, RCS-4, as well as ∆9-tetrahydrocannabinol following pulmonary administration to pigsSchaefer, Nadine; Kröll, Ann-Katrin; Körbel, Christina; Laschke, Matthias W.; Menger, Michael D.; Maurer, Hans H.; Meyer, Markus R.; Schmidt, Peter H.
article2020Toxicometabolomics of the new psychoactive substances α-PBP and α-PEP studied in HepaRG cell incubates by means of untargeted metabolomics revealed unexpected amino acid adductsManier, Sascha K.; Wagmann, Lea; Flockerzi, Veit; Meyer, Markus R.
article2020Toxicokinetics and toxicodynamics of the fentanyl homologs cyclopropanoyl-1-benzyl-4´-fluoro-4-anilinopiperidine and furanoyl-1-benzyl-4-anilinopiperidineGampfer, Tanja M.; Wagmann, Lea; Park, Yu Mi; Cannaert, Annelies; Herrmann, Jennifer; Fischmann, Svenja; Westphal, Folker; Stove, Christophe P.; Meyer, Markus R.; Müller, Rolf
article2019Studies on the in vitro and in vivo metabolism of the synthetic opioids U-51754, U-47931E, and methoxyacetylfentanyl using hyphenated high-resolution mass spectrometryNordmeier, Frederike; Richter, Lilian H. J.; Schmidt, Peter H.; Schaefer, Nadine; Meyer, Markus R.
article2019Untargeted metabolomics by high resolution mass spectrometry coupled to normal and reversed phase liquid chromatography as a tool to study the in vitro biotransformation of new psychoactive substancesManier, Sascha K.; Keller, Andreas; Schäper, Jan; Meyer, Markus R.
article2019In vitro metabolic fate of nine LSD-based new psychoactive substances and their analytical detectability in different urinary screening proceduresWagmann, Lea; Richter, Lilian; Kehl, Tobias; Wack, Franziska; Pettersson Bergstrand, Madeleine; Brandt, Simon D.; Stratford, Simon; Maurer, Hans H.; Meyer, Markus R.
article2019Toxicokinetic studies of the four new psychoactive substances 4-chloroethcathinone, N-ethylnorpentylone, N-ethylhexedrone, and 4-fluoro-alpha-pyrrolidinohexiophenoneWagmann, Lea; Manier, Sascha K.; Eckstein, Niels; Maurer, Hans H.; Meyer, Markus R.
article2019The metabolic fate of two new psychoactive substances - 2-aminoindane and N-methyl-2-aminoindane - studied in vitro and in vivo to support drug testingManier, Sascha K.; Felske, Christina; Eckstein, Niels; Meyer, Markus R.
article2019Evaluation of novel organosilane modifications of paper spray mass spectrometry substrates for analyzing polar compoundsBambauer, Thomas P.; Maurer, Hans H.; Weber, Armin A.; Hannig, Matthias; Pütz, Norbert; Koch, Marcus; Manier, Sascha K.; Schneider, Marc; Meyer, Markus R.
article2019Method development for quantitative determination of seven statins including four active metabolites by means of high-resolution tandem mass spectrometry applicable for adherence testing and therapeutic drug monitoringWagmann, Lea; Hemmer, Selina; Caspar, Achim T.; Meyer, Markus
article2019Phenethylamine-derived new psychoactive substances 2C-E-FLY, 2C-EF-FLY, and 2C-T-7-FLY: Investigations on their metabolic fate including isoenzyme activities and their toxicological detectability in urine screeningsWagmann, Lea; Hempel, Nora; Richter, Lilian H. J.; Brandt, Simon D.; Stratford, Alexander; Meyer, Markus R.
article2019Toxicokinetics and analytical toxicology of the abused opioid U-48800 - in vitro metabolism, metabolic stability, isozyme mapping, and plasma protein bindingGampfer, Tanja M.; Richter, Lilian H. J.; Schäper, Jan; Wagmann, Lea; Meyer, Markus R.
article2018Different in vitro and in vivo tools for elucidating the human metabolism of alpha-cathinone-derived drugs of abuseManier, Sascha K.; Richter, Lilian; Schäper, Jan; Maurer, Hans H.; Meyer, Markus R.
article2018Interactions of phenethylamine‐derived psychoactive substances of the 2C‐series with human monoamine oxidasesWagmann, Lea; Brandt, Simon D.; Stratford, Alexander; Maurer, Hans H.; Meyer, Markus R.
article2018Inhibition and stimulation of the human breast cancer resistance protein as in vitro predictor of drug–drug interactions of drugs of abuseWagmann, Lea; Maurer, Hans H.; Meyer, Markus R.
article2018Can toxicokinetics of (synthetic) cannabinoids in pigs after pulmonary administration be upscaled to humans by allometric techniques?Schaefer, Nadine; Wojtyniak, Jan-Georg; Kroell, Ann-Katrin; Koerbel, Christina; Laschke, Matthias W.; Lehr, Thorsten; Menger, Michael D.; Maurer, Hans H.; Meyer, Markus R.; Schmidt, Peter H.
article2018Automated optimization of XCMS parameters for improved peak picking of liquid chromatography-mass spectrometry data using the coefficient of variation and parameter sweeping for untargeted metabolomicsManier, Sascha K.; Keller, Andreas; Meyer, Markus R.
article2017An easy and fast adenosine 5'-diphosphate quantification procedure based on hydrophilic interaction liquid chromatography-high resolution tandem mass spectrometry for determination of the in vitro adenosine 5'-triphosphatase activity of the human breast cancer resistance protein ABCG2Wagmann, Lea; Maurer, Hans H.; Meyer, Markus R.
article2017In vitro monoamine oxidase inhibition potential of alpha-methyltryptamine analog new psychoactive substances for assessing possible toxic risksWagmann, Lea; Brandt, Simon D.; Kavanagh, Pierce V.; Maurer, Hans H.; Meyer, Markus R.
article2016What is the contribution of human FMO3 in the N-oxygenation of selected therapeutic drugs and drugs of abuse?Wagmann, Lea; Meyer, Markus R.; Maurer, Hans H.
Welcome
ORCID: iD icon https://orcid.org/0000-0003-4377-6784
Name:Meyer, Markus
Faculty: M - Medizinische Fakultät
Department: M - Experimentelle und Klinische Pharmakologie und Toxikologie
Professorship:M - Prof. Dr. Markus Meyer
Display style: