| Dokumenttyp | Erscheinungsjahr | Titel | Autoren | Herausgeber |
|---|
| article | 2024 | Spray drying of a zinc complexing agent for inhalation therapy of pulmonary fibrosis | Stella, Justin; Abdelaal, Maryam Ayman Mohamed Ezzat; Kamal, Mohamed Ashraf Mostafa; Shehu, Kristela; Alhayek, Alaa; Haupenthal, Jörg; Hirsch, Anna K.; Schneider, Marc | |
| article | 2023 | Inhibitors of the Elastase LasB for the Treatment of Pseudomonas aeruginosa Lung Infections | Konstantinović, Jelena; Kany, Andreas M.; Alhayek, Alaa; Abdelsamie, Ahmed S.; Sikandar, Asfandyar; Voos, Katrin; Yiwen, Yao; Andreas, Anastasia; Shafiei, Roya; Loretz, Brigitta; Schönauer, Esther; Bals, Robert; Brandstetter, Hans; Hartmann, Rolf W.; Ducho, Christian; Lehr, Claus-Michael; Beißwenger, Christoph; Müller, Rolf; Rox, Katharina; Haupenthal, Jörg; Hirsch, Anna | |
| article | 2022 | First crystal structures of 1-deoxy-D-xylulose 5-phosphate synthase (DXPS) from Mycobacterium tuberculosis indicate a distinct mechanism of intermediate stabilization | Gierse, Robin M.; Oerlemans, Rick; Reddem, Eswar R.; Gawriljuk, Victor O.; Alhayek, Alaa; Baitinger, Dominik; Jakobi, Harald; Laber, Bernd; Lange, Gudrun; Hirsch, Anna K. H.; Groves, Matthew R. | |
| article | 2022 | Structure-Based Design of α-Substituted Mercaptoacetamides as Inhibitors of the Virulence Factor LasB from Pseudomonas aeruginosa | Kaya, Cansu; Walter, Isabell; Alhayek, Alaa; Shafiei, Roya; Jézéquel, Gwenaëlle; Andreas, Anastasia; Konstantinović, Jelena; Schönauer, Esther; Sikandar, Asfandyar; Haupenthal, Jörg; Müller, Rolf; Brandstetter, Hans; Hartmann, Rolf W.; Hirsch, Anna K. H. | |
| Other | 2022 | N-Aryl-2-iso-butylmercaptoacetamides: the discovery of highly potent and selective inhibitors of Pseudomonas aeruginosa virulence factor LasB and Clostridium histolyticum virulence factor ColH | Voos, Katrin; Yahiaoui, Samir; Konstantinović, Jelena; Schönauer, Esther; Alhayek, Alaa; Sikandar, Asfandyar; Si Chaib, Khadidja; Ramspoth, Tizian; Rox, Katharina; Haupenthal, Jörg; Köhnke, Jesko; Brandstetter, Hans; Ducho, Christian; Hirsch, Anna | |
| article | 2021 | Identification of a 1-deoxy-D-xylulose-5-phosphate synthase (DXS) mutant with improved crystallographic properties | Gierse, Robin M.; Reddem, Eswar R.; Alhayek, Alaa; Baitinger, Dominik; Zhoor, Hamid; Jakobi, Harald; Laber, Bernd; Lange, Gudrun; Hirsch, Anna K. H.; Groves, Matthew R. | |
| article | 2021 | Hit-optimization using target-directed dynamic combinatorial chemistry : development of inhibitors of the anti-infective target 1-deoxy-d-xylulose-5-phosphate synthase | Jumde, Ravindra P.; Guardigni, Melissa; Gierse, Robin M.; Alhayek, Alaa; Zhu, Di; Hamid, Zhoor; Johannsen, Sandra; Elgaher, Walid A. M.; Neusens, Philipp J.; Nehls, Christian; Haupenthal, Jörg; Reiling, Norbert; Hirsch, Anna K. H. | |
| article | 2021 | Substrate-Inspired Fragment Merging and Growing Affords Efficacious LasB Inhibitors | Kaya, Cansu; Walter, Isabell; Yahiaoui, Samir; Sikandar, Asfandyar; Alhayek, Alaa; Konstantinović, Jelena; Kany, Andreas M.; Haupenthal, Jörg; Köhnke, Jesko; Hartmann, Rolf W.; Hirsch, Anna K. H. | |
| article | 2020 | N-Aryl-3-mercaptosuccinimides as Antivirulence Agents Targeting Pseudomonas aeruginosa Elastase and Clostridium Collagenases | Konstantinović, Jelena; Yahiaoui, Samir; Alhayek, Alaa; Haupenthal, Jörg; Schönauer, Esther; Andreas, Anastasia; Kany, Andreas M.; Müller, Rolf; Koehnke, Jesko; Berger, Fabian K.; Bischoff, Markus; Hartmann, Rolf W.; Brandstetter, Hans; Hirsch, Anna K. H. | |
| article | 2020 | Protein-Templated Hit Identification through an Ugi Four-Component Reaction | Mancini, Federica; Unver, M. Yagiz; Elgaher, Walid A. M.; Jumde, Varsha R.; Alhayek, Alaa; Lukat, Peer; Herrmann, Jennifer; Witte, Martin D.; Köck, Matthias; Blankenfeldt, Wulf; Müller, Rolf; Hirsch, Anna K. H. | |
