| Dokumenttyp | Erscheinungsjahr | Titel | Autoren | Herausgeber |
|---|
| article | 2024 | Immunomodulation by glucocorticoid-induced leucine zipper in macrophages: enhanced phagocytosis, protection from pyroptosis, and altered mitochondrial function | Legroux, Thierry M.; Schymik, Hanna S.; Gasparoni, Gilles; Mohammadi, Saeed; Walter, Jörn; Libert, Claude; Diesel, Britta; Hoppstädter, Jessica; Kiemer, Alexandra K. | |
| article | 2024 | The RNA binding protein IGF2BP2/IMP2 alters the cargo of cancer cell-derived extracellular vesicles supporting tumor-associated macrophages | Mashayekhi, Vida; Schomisch, Annika; Rasheed, Sari; Aparicio-Puerta, Ernesto; Risch, Timo; Yildiz, Daniela; Koch, Marcus; Both, Simon; Ludwig, Nicole; Legroux, Thierry M.; Keller, Andreas; Müller, Rolf; Fuhrmann, Gregor; Hoppstädter, Jessica; Kiemer, Alexandra K. | |
| article | 2024 | Gene Editing and Small Molecule Inhibitors of the RNA Binding Protein IGF2BP2/IMP2 Show its Potential as an Anti-Cancer Drug Target | Chanda, Shilpee; Lepikhov, Konstantin; Dahlem, Charlotte; Schymik, Hanna S.; Hoppstädter, Jessica; Geber, An-Kristin; Wagner, Konrad; Kessler, Sonja M.; Empting, Martin; Kiemer, Alexandra | |
| article | 2024 | C-Myc/H19/miR-29b axis downregulates nerve/glial (NG)2 expression in glioblastoma multiforme | Boewe, Anne S.; Wrublewsky, Selina; Hoppstädter, Jessica; Götz, Claudia; Kiemer, Alexandra K.; Menger, Michael D.; Laschke, Matthias W.; Ampofo, Emmanuel | |
| article | 2023 | Alterations in the hepatocyte epigenetic landscape in steatosis | Maji, Ranjan Kumar; Czepukojc, Beate; Scherer, Michael; Tierling, Sascha; Cadenas, Cristina; Gianmoena, Kathrin; Gasparoni, Nina; Nordström, Karl; Gasparoni, Gilles; Laggai, Stephan; Yang, Xinyi; Sinha, Anupam; Ebert, Peter; Falk-Paulsen, Maren; Kinkley, Sarah; Hoppstädter, Jessica; Chung, Ho-Ryun; Rosenstiel, Philip; Hengstler, Jan G; Walter, Jörn Erik; Schulz, Marcel H.; Kessler, Sonja M.; Kiemer, Alexandra | |
| article | 2023 | Nanostructured Microparticles Repolarize Macrophages and Induce Cell Death in an In Vitro Model of Tumour-Associated Macrophages | Al-Fityan, Salma; Diesel, Britta; Fischer, Thorben; Ampofo, Emmanuel; Schomisch, Annika; Mashayekhi, Vida; Schneider, Marc; Kiemer, Alexandra K. | |
| article | 2023 | Endotoxin Tolerance Acquisition and Altered Hepatic Fatty Acid Profile in Aged Mice | Wiesenthal, Amanda A.; Legroux, Thierry M.; Richter, Chris; Junker, Björn H.; Hecksteden, Anne; Kessler, Sonja M.; Hoppstädter, Jessica; Kiemer, Alexandra K. | |
| article | 2023 | Control of CAR-T cell activity in space and time: the next level of anti-tumor action | Hoppstädter, Jessica; Kiemer, Alexandra K. | |
| article | 2023 | Cell-Derived Vesicles for Antibiotic Delivery-Understanding the Challenges of a Biogenic Carrier System | Heinrich, Eilien; Hartwig, Olga; Walt, Christine; Kardani, Arefeh; Koch, Marcus; Jahromi, Leila Pourtalebi; Hoppstädter, Jessica; Kiemer, Alexandra K.; Loretz, Brigitta; Lehr, Claus-Michael; Fuhrmann, Gregor | |
| article | 2023 | A combined computational and functional approach identifies IGF2BP2 as a driver of chemoresistance in a wide array of pre-clinical models of colorectal cancer | Kendzia, Sandra; Franke, Susanne; Kröhler, Tarek; Golob-Schwarzl, Nicole; Schweiger, Caroline; Toeglhofer, Anna M.; Skofler, Christina; Uranitsch, Stefan; El-Heliebi, Amin; Fuchs, Julia; Punschart, Andreas; Stiegler, Philipp; Keil, Marlen; Hoffmann, Jens; Henderson, David; Lehrach, Hans; Yaspo, Marie-Laure; Reinhard, Christoph; Schäfer, Reinhold; Keilholz, Ulrich; Regenbrecht, Christian; Schicho, Rudolf; Fickert, Peter; Lax, Sigurd F.; Erdmann, Frank; Schulz, Marcel H.; Kiemer, Alexandra K.; Haybaeck, Johannes; Kessler, Sonja M. | |
| article | 2022 | Identification and Biochemical Characterization of Pyrrolidinediones as Novel Inhibitors of the Bacterial Enzyme MurA | Fathalla, Reem K.; Fröhner, Wolfgang; Bader, Chantal D.; Fischer, Patrick D.; Dahlem, Charlotte; Chatterjee, Deep; Mathea, Sebastian; Kiemer, Alexandra K.; Arthanari, Haribabu; Müller, Rolf; Abdel-Halim, Mohammad; Ducho, Christian; Engel, Matthias | |
| article | 2022 | Induction of Liver Size Reduction in Zebrafish Larvae by the Emerging Synthetic Cannabinoid 4F-MDMB-BINACA and Its Impact on Drug Metabolism | Park, Yu Mi; Dahlem, Charlotte; Meyer, Markus R.; Kiemer, Alexandra K.; Müller, Rolf; Herrmann, Jennifer | |
| article | 2022 | Characterization of Anti-Cancer Activities of Violacein: Actions on Tumor Cells and the Tumor Microenvironment | Dahlem, Charlotte; Chanda, Shilpee; Hemmer, Jan; Schymik, Hanna S.; Kohlstedt, Michael; Wittmann, Christoph; Kiemer, Alexandra K. | |
| article | 2022 | Nano-in-Microparticles for Aerosol Delivery of Antibiotic-Loaded, Fucose-Derivatized, and Macrophage-Targeted Liposomes to Combat Mycobacterial Infections: In Vitro Deposition, Pulmonary Barrier Interactions, and Targeted Delivery | Huck, Benedikt C.; Thiyagarajan, Durairaj; Bali, Aghiad; Boese, Annette; Besecke, Karen F. W.; Hozsa, Constantin; Gieseler, Robert K.; Furch, Marcus; Carvalho-Wodarz, Cristiane; Waldow, Franziska; Schwudke, Dominik; Metelkina, Olga; Titz, Alexander; Huwer, Hanno; Schwarzkopf, Konrad; Hoppstädter, Jessica; Kiemer, Alexandra Kathrin; Koch, Marcus; Loretz, Brigitta; Lehr, Claus-Michael | |
| article | 2022 | Comment on: The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ | Schymik, Hanna S.; Dahlem, Charlotte; Barghash, Ahmad; Kiemer, Alexandra K. | |
| article | 2022 | First Small-Molecule Inhibitors Targeting the RNA-Binding Protein IGF2BP2/IMP2 for Cancer Therapy | Dahlem, Charlotte; Abuhaliema, Ali; Kessler, Sonja M.; Kröhler, Tarek; Zoller, Ben G. E.; Chanda, Shilpee; Wu, Yingwen; Both, Simon; Müller, Fabian; Lepikhov, Konstantin; Kirsch, Susanne H.; Laggai, Stephan; Müller, Rolf; Empting, Martin; Kiemer, Alexandra K. | |
| article | 2022 | Kupffer cells are protective in alcoholic steatosis | Köhler, Nikolai; Höring, Marcus; Czepukojc, Beate; Rose, Tim Daniel; Buechler, Christa; Kröhler, Tarek; Haybaeck, Johannes; Liebisch, Gerhard; Pauling, Josch K.; Kessler, Sonja M.; Kiemer, Alexandra K. | |
| article | 2022 | Yields and Immunomodulatory Effects of Pneumococcal Membrane Vesicles Differ with the Bacterial Growth Phase | Mehanny, Mina; Kroniger, Tobias; Koch, Marcus; Hoppstädter, Jessica; Becher, Dörte; Kiemer, Alexandra K.; Lehr, Claus-Michael; Fuhrmann, Gregor | |
| article | 2022 | Spray-dried pneumococcal membrane vesicles are promising candidates for pulmonary immunization | Mehanny Habeeb Kaldas, Mina; Boese, Annette; Bornamehr, Behnoosh; Hoppstädter, Jessica; Presser, Volker; Kiemer, Alexandra K.; Lehr, Claus-Michael; Fuhrmann, Gregor | |
| article | 2022 | The inherent antibiotic activity of myxobacteria-derived autofluorescent outer membrane vesicles is switched on and off by light stimulation | Lapuhs, Philipp; Heinrich, Eilien; Garcia, Ronald; Goes Conceicao, Adriely; Frank, Nicolas Alexander; Bollenbach, Lukas; Stibane, Veronika; Kuhn, Thomas; Koch, Marcus; Kiemer, Alexandra K.; Müller, Rolf; Fuhrmann, Kathrin; Fuhrmann, Gregor | |
| article | 2021 | Statins and Bempedoic Acid: Different Actions of Cholesterol Inhibitors on Macrophage Activation | Linnenberger, Rebecca; Hoppstädter, Jessica; Wrublewsky, Selina; Ampofo, Emmanuel; Kiemer, Alexandra K. | |
| article | 2021 | Chemical composition and biological activities of Valeriana dioscoridis SM. roots | Sen-Utsukarci, Burcu; Kessler, Sonja M.; Akbal-Dagistan, Ozlem; Estep, Alden S.; Tabanca, Nurhayat; Kurkcuoglu, Mine; Demirci-Kayiran, Serpil; Eroglu-Ozkan, Esra; Gul, Zulfiye; Bardakci, Hilal; Becnel, James; Kiemer, Alexandra K.; Mat, Afife; Baser, Kemal Husnu Can | |
| article | 2020 | Baikalomycins A-C, New Aquayamycin-Type Angucyclines Isolated from Lake Baikal Derived Streptomyces sp. IB201691-2A | Voitsekhovskaia, Irina; Paulus, Constanze; Dahlem, Charlotte; Rebets, Yuriy; Nadmid, Suvd; Zapp, Josef; Axenov-Gribanov, Denis; Rückert, Christian; Timofeyev, Maxim; Kalinowski, Jörn; Kiemer, Alexandra K.; Luzhetskyy, Andriy | |
| article | 2020 | The glucocorticoid-induced leucine zipper mediates statin-induced muscle damage | Hoppstädter, Jessica; Valbuena Perez, Jenny Vanessa; Linnenberger, Rebecca; Dahlem, Charlotte; Legroux, Thierry M.; Hecksteden, Anne; Tse, William K. F.; Flamini, Sara; Andreas, Anastasia; Herrmann, Jennifer; Herr, Christian; Müller, Rolf; Meyer, Tim; Bals, Robert; Riccardi, Carlo; Bruscoli, Stefano; Kiemer, Alexandra K. | |
| article | 2020 | Myxobacteria-Derived Outer Membrane Vesicles: Potential Applicability Against Intracellular Infections | Goes, Adriely; Lapuhs, Philipp; Kuhn, Thomas; Schulz, Eilien; Richter, Robert; Panter, Fabian; Dahlem, Charlotte; Koch, Marcus; Garcia, Ronald; Kiemer, Alexandra K.; Müller, Rolf; Fuhrmann, Gregor | |
| article | 2020 | Thioholgamide A, a New Anti-Proliferative Anti-Tumor Agent, Modulates Macrophage Polarization and Metabolism | Dahlem, Charlotte; Siow, Wei Xiong; Lopatniuk, Maria; Tse, William K. F.; Kessler, Sonja M.; Kirsch, Susanne H.; Hoppstädter, Jessica; Vollmar, Angelika M.; Müller, Rolf; Luzhetskyy, Andriy; Bartel, Karin; Kiemer, Alexandra K. | |
| article | 2020 | Blockade of an innate immune amplifier to fight immune hyperactivation in COVID-19? | Kiemer, Alexandra K. | |
| article | 2020 | Metabolic implication of tigecycline as an efficacious second-line treatment for sorafenib-resistant hepatocellular carcinoma | Meßner, Martina; Schmitt, Sabine; Ardelt, Maximilian A.; Fröhlich, Thomas; Müller, Martin; Pein, Helmut; Huber-Cantonati, Petra; Ortler, Carina; Koenig, Lars M.; Zobel, Lena; Koeberle, Andreas; Arnold, Georg J.; Rothenfußer, Simon; Kiemer, Alexandra K.; Gerbes, Alexander L.; Zischka, Hans; Vollmar, Angelika M; Pachmayr, Johanna | |
| article | 2019 | Amplified Host Defense by Toll-Like Receptor-Mediated Downregulation of the Glucocorticoid-Induced Leucine Zipper (GILZ) in Macrophages | Hoppstädter, Jessica; Diesel, Britta; Linnenberger, Rebecca; Hachenthal, Nina; Flamini, Sara; Minet, Marie; Leidinger, Petra; Backes, Christina; Grässer, Friedrich; Meese, Eckart; Bruscoli, Stefano; Riccardi, Carlo; Huwer, Hanno; Kiemer, Alexandra | |
| article | 2019 | Lack of Kupffer cell depletion in diethylnitrosamine-induced hepatic inflammation | Kessler, Sonja M.; Hoppstädter, Jessica; Hosseini, Kevan; Laggai, Stephan; Haybaeck, Johannes; Kiemer, Alexandra | |
| article | 2019 | High Keratin 8/18 Ratio Predicts Aggressive Hepatocellular Cancer Phenotype | Golob-Schwarzl, Nicole; Bettermann, Kira; Mehta, Anita Kuldeep; Kessler, Sonja M.; Unterluggauer, Julia; Krassnig, Stefanie; Kojima, Kensuke; Chen, Xintong; Hoshida, Yujin; Bardeesy, Nabeel M.; Müller, Heimo; Svendova, Vendula; Schimek, Michael G.; Diwoky, Clemens; Lipfert, Alexandra; Mahajan, Vineet; Stumptner, Cornelia; Thüringer, Andrea; Fröhlich, Leopold F.; Stojakovic, Tatjana; Nilsson, K.P.R.; Kolbe, Thomas; Rülicke, Thomas; Magin, Thomas M.; Strnad, Pavel; Kiemer, Alexandra; Moriggl, Richard; Haybaeck, Johannes | |
| article | 2019 | The mRNA-binding Protein TTP/ZFP36 in Hepatocarcinogenesis and Hepatocellular Carcinoma | Kröhler, Tarek; Kessler, Sonja M.; Hosseini, Kevan; List, Markus; Barghash, Ahmad; Patial, Sonika; Laggai, Stephan; Gemperlein, Katja; Haybaeck, Johannes; Müller, Rolf; Helms, Volkhard; Schulz, Marcel H.; Hoppstädter, Jessica; Blackshear, Perry J.; Kiemer, Alexandra K. | |
| article | 2019 | Mechanical strain mimicking breathing amplifies alterations in gene expression induced by SiO2 NPs in lung epithelial cells | Schmitz, Carmen; Welck, Jennifer; Tavernaro, Isabella; Grinberg, Marianna; Rahnenführer, Jörg; Kiemer, Alexandra; van Thriel, Christoph; Hengstler, Jan G.; Kraegeloh, Annette | |
| article | 2019 | Targeted delivery of functionalized PLGA nanoparticles to macrophages by complexation with the yeast Saccharomyces cerevisiae | Kiefer, Ruth; Jurisic, Marijas; Dahlem, Charlotte; Koch, Marcus; Schmitt, Manfred J.; Kiemer, Alexandra K.; Schneider, Marc; Breinig, Frank | |
| article | 2019 | Hepatocellular Carcinoma and Nuclear Paraspeckles: Induction in Chemoresistance and Prediction for Poor Survival | Kessler, Sonja M.; Hosseini, Kevan; Hussein, Usama Khamis; Kim, Kyoung Min; List, Markus; Schultheiß, Christina S.; Schulz, Marcel H.; Laggai, Stephan; Jang, Kyu Yun; Kiemer, Alexandra | |
| article | 2019 | Toll-Like Receptor 2 Release by Macrophages: An Anti-inflammatory Program Induced by Glucocorticoids and Lipopolysaccharide | Hoppstädter, Jessica; Dembek, Anna; Linnenberger, Rebecca; Dahlem, Charlotte; Barghash, Ahmad; Fecher-Trost, Claudia; Fuhrmann, Gregor; Koch, Marcus; Kraegeloh, Annette; Huwer, Hanno; Kiemer, Alexandra | |
| article | 2019 | IGF2 mRNA Binding Protein 2 Transgenic Mice Are More Prone to Develop a Ductular Reaction and to Progress Toward Cirrhosis | Czepukojc, Beate; Abuhaliema, Ali; Barghash, Ahmad; Tierling, Sascha; Naß, Norbert; Simon, Yvette; Körbel, Christina; Cadenas, Cristina; van Hul, Noemi; Sachinidis, Agapios; Hengstler, Jan G; Helms, Volkhard; Laschke, Matthias W.; Walter, Jörn; Haybaeck, Johannes; Leclercq, Isabelle; Kiemer, Alexandra; Kessler, Sonja M. | |
| article | 2019 | CRUP : a comprehensive framework to predict condition-specific regulatory units | Ramisch, Anna; Heinrich, Verena; Glaser, Laura V.; Fuchs, Alisa; Yang, Xinyi; Benner, Philipp; Schöpflin, Robert; Li, Na; Kinkley, Sarah; Römer-Hillmann, Anja; Longinotto, John; Heyne, Steffen; Czepukojc, Beate; Kessler, Sonja M.; Kiemer, Alexandra K.; Cadenas, Cristina; Arrigoni, Laura; Gasparoni, Nina; Manke, Thomas; Pap, Thomas; Pospisilik, John A.; Hengstler, Jan; Walter, Jörn; Meijsing, Sebastiaan H.; Chung, Ho-Ryun; Vingron, Martin | |
| article | 2019 | Perquinolines A-C: Unprecedented Bacterial Tetrahydroisoquinolines Involving an Intriguing Biosynthesis | Rebets, Yuriy; Nadmid, Suvd; Paulus, Constanze; Dahlem, Charlotte; Herrmann, Jennifer; Hübner, Harald; Rückert, Christian; Kiemer, Alexandra K.; Gmeiner, Peter; Kalinowski, Jörn; Müller, Rolf; Luzhetskyy, Andriy | |
| article | 2019 | The Cytotoxicity and Insecticidal Activity of Extracts from Delphinium formosum Boiss. & Huet | Sen-Utsukarci, Burcu; Tabanca, Nurhayat; Estep, Alden S.; Akbal-Dagistan, Ozlem; Kessler, Sonja M.; Ozturk, Zehra; Becnel, James; Kiemer, Alexandra K.; Mat, Afife | |
| article | 2018 | Hsp72 protects against liver injury via attenuation of hepatocellular death, oxidative stress, and JNK signaling | Levada, Kateryna; Guldiken, Nurdan; Zhang, Xiaoji; Vella, Giovanna; Mo, Fa-Rong; James, Laura P.; Haybaeck, Johannes; Kessler, Sonja M.; Kiemer, Alexandra; Ott, Thomas; Hartmann, Daniel; Hüser, Norbert; Ziol, Marianne; Trautwein, Christian; Strnad, Pavel | |
| article | 2018 | A Reinvestigation of Norditerpenoid Alkaloids from the Roots of Delphinium formosum | Sen-Utsukarci, B.; Zapp, J.; Kiemer, Alexandra; Mericli, A. H. | |
| article | 2018 | Copy Number Alterations in Tumor Genomes Deleting Antineoplastic Drug Targets Partially Compensated by Complementary Amplifications | Tran, Ha Vu; Kiemer, Alexandra; Helms, Volkhard | |
| article | 2017 | The long non-coding RNA H19 suppresses carcinogenesis and chemoresistance in hepatocellular carcinoma | Schultheiss, Christina S.; Laggai, Stephan; Czepukojc, Beate; Hussein, Usama K.; List, Markus; Barghash, Ahmad; Tierling, Sascha; Hosseini, Kevan; Golob-Schwarzl, Nicole; Pokorny, Juliane; Hachenthal, Nina; Schulz, Marcel; Helms, Volkhard; Walter, Jörn Erik; Zimmer, Vincent; Lammert, Frank; Bohle, Rainer M.; Dandolo, Luisa; Haybaeck, Johannes; Kiemer, Alexandra; Kessler, Sonja M. | |
| article | 2017 | Yeast-mediated mRNA delivery polarizes immuno-suppressive macrophages towards an immuno-stimulatory phenotype | Seif, Michelle; Hoppstädter, Jessica; Breinig, Frank; Kiemer, Alexandra | |
| article | 2017 | IMP2/IGF2BP2 expression, but not IMP1 and IMP3, predicts poor outcome in patients and high tumor growth rate in xenograft models of gallbladder cancer | Kessler, Sonja M.; Lederer, Eva; Laggai, Stephan; Golob-Schwarzl, Nicole; Hosseini, Kevan; Petzold, Johannes; Schweiger, Caroline; Reihs, Robert; Keil, Marlen; Hoffmann, Jens; Mayr, Christian; Kiesslich, Tobias; Pichler, Martin; Kim, Kyung Sik; Rhee, Hyungjin; Park, Young Nyun; Lax, Sigurd; Obrist, Peter; Kiemer, Alexandra; Haybaeck, Johannes | |
| article | 2017 | Hepatic interleukin-6 production is maintained during endotoxin tolerance and facilitates lipid accumulation | Dembek, Anna; Laggai, Stephan; Kessler, Sonja M.; Czepukojc, Beate; Simon, Yvette; Kiemer, Alexandra; Hoppstädter, Jessica | |
| article | 2014 | Fatty Acid Elongation in Non-Alcoholic Steatohepatitis and Hepatocellular Carcinoma | Keßler, Sonja M.; Simon, Yvette; Gemperlein, Katja; Gianmoena, Kathrin; Cadenas, Cristina; Zimmer, Vincent; Pokorny, Juliane; Barghash, Ahmad; Helms, Volkhard; van Rooijen, Nico; Bohle, Rainer M.; Lammert, Frank; Hengstler, Jan G.; Mueller, Rolf; Haybaeck, Johannes; Kiemer, Alexandra K. | |
https://orcid.org/0000-0002-7224-9900