| Dokumenttyp | Erscheinungsjahr | Titel | Autoren | Herausgeber |
|---|
| article | 2022 | First crystal structures of 1-deoxy-D-xylulose 5-phosphate synthase (DXPS) from Mycobacterium tuberculosis indicate a distinct mechanism of intermediate stabilization | Gierse, Robin M.; Oerlemans, Rick; Reddem, Eswar R.; Gawriljuk, Victor O.; Alhayek, Alaa; Baitinger, Dominik; Jakobi, Harald; Laber, Bernd; Lange, Gudrun; Hirsch, Anna K. H.; Groves, Matthew R. | |
| article | 2022 | Discovery of novel drug-like antitubercular hits targeting the MEP pathway enzyme DXPS by strategic application of ligand-based virtual screening | Zhu, Di; Johannsen, Sandra; Masini, Tiziana; Simonin, Céline; Haupenthal, Jörg; Illarionov, Boris; Andreas, Anastasia; Awale, Mahendra; Gierse, Robin M.; van der Laan, Tridia; van der Vlag, Ramon; Nasti, Rita; Poizat, Mael; Buhler, Eric; Reiling, Norbert; Müller, Rolf; Fischer, Markus; Reymond, Jean-Louis; Hirsch, Anna K. H. | |
| doctoralThesis | 2022 | Design, synthesis and structural characterisation of inhibitors of 1-Deoxy-D-xylulose-5-phosphate Synthase | Gierse, Robin Matthias | |
| article | 2021 | Identification of a 1-deoxy-D-xylulose-5-phosphate synthase (DXS) mutant with improved crystallographic properties | Gierse, Robin M.; Reddem, Eswar R.; Alhayek, Alaa; Baitinger, Dominik; Zhoor, Hamid; Jakobi, Harald; Laber, Bernd; Lange, Gudrun; Hirsch, Anna K. H.; Groves, Matthew R. | |
| article | 2021 | Hit-optimization using target-directed dynamic combinatorial chemistry : development of inhibitors of the anti-infective target 1-deoxy-d-xylulose-5-phosphate synthase | Jumde, Ravindra P.; Guardigni, Melissa; Gierse, Robin M.; Alhayek, Alaa; Zhu, Di; Hamid, Zhoor; Johannsen, Sandra; Elgaher, Walid A. M.; Neusens, Philipp J.; Nehls, Christian; Haupenthal, Jörg; Reiling, Norbert; Hirsch, Anna K. H. | |
