Please use this identifier to cite or link to this item:
doi:10.22028/D291-43994 | Title: | Syntheses of bottromycin derivatives via Ugi-reactions and Matteson homologations |
| Author(s): | Bickel, Etienne Kazmaier, Uli |
| Language: | English |
| Title: | Organic & Biomolecular Chemistry |
| Volume: | 22 |
| Issue: | 44 |
| Pages: | 8811-8816 |
| Publisher/Platform: | Royal Society of Chemistry |
| Year of Publication: | 2024 |
| DDC notations: | 500 Science |
| Publikation type: | Journal Article |
| Abstract: | New bottromycin derivatives have been prepared using flexible Ugi and Matteson reactions. The Ugi reaction allows the fast and direct assembly of sterically hindered peptide fragments, while the Matteson homologation is excellently suited for the stereoselective synthesis of unusual amino acids like β-methylphenylalanine. Some of the new compounds show excellent activity against Streptococcus pneumoniae. |
| DOI of the first publication: | 10.1039/D4OB01373E |
| URL of the first publication: | https://doi.org/10.1039/D4OB01373E |
| Link to this record: | urn:nbn:de:bsz:291--ds-439942 hdl:20.500.11880/39366 http://dx.doi.org/10.22028/D291-43994 |
| ISSN: | 1477-0539 1477-0520 |
| Date of registration: | 13-Jan-2025 |
| Description of the related object: | Supplementary information |
| Related object: | https://www.rsc.org/suppdata/d4/ob/d4ob01373e/d4ob01373e1.pdf |
| Faculty: | NT - Naturwissenschaftlich- Technische Fakultät |
| Department: | NT - Chemie |
| Professorship: | NT - Prof. Dr. Uli Kazmaier |
| Collections: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
Files for this record:
| File | Description | Size | Format | |
|---|---|---|---|---|
| d4ob01373e.pdf | 691,73 kB | Adobe PDF | View/Open |
This item is licensed under a Creative Commons License
