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doi:10.22028/D291-42698 | Title: | Unlocking the Potential: immune functions of oligodendrocyte precursor cells |
| Author(s): | Haroon, Amr Seerapu, Harsha Fang, Li-Pao Weß, Jakob Heinrich Bai, Xianshu |
| Language: | English |
| Title: | Frontiers in Immunology |
| Volume: | 15 |
| Publisher/Platform: | Frontiers |
| Year of Publication: | 2024 |
| Free key words: | oligodendrocyte precursor cells immune functions immunomodulation CNS injury phagocytosis multiple sclerosis brain injury |
| DDC notations: | 610 Medicine and health |
| Publikation type: | Journal Article |
| Abstract: | Oligodendrocyte precursor cells (OPCs) have long been regarded as progenitors of oligodendrocytes, yet recent advances have illuminated their multifaceted nature including their emerging immune functions. This review seeks to shed light on the immune functions exhibited by OPCs, spanning from phagocytosis to immune modulation and direct engagement with immune cells across various pathological scenarios. Comprehensive understanding of the immune functions of OPCs alongside their other roles will pave the way for targeted therapies in neurological disorders. |
| DOI of the first publication: | 10.3389/fimmu.2024.1425706 |
| URL of the first publication: | https://doi.org/10.3389/fimmu.2024.1425706 |
| Link to this record: | urn:nbn:de:bsz:291--ds-426982 hdl:20.500.11880/38299 http://dx.doi.org/10.22028/D291-42698 |
| ISSN: | 1664-3224 |
| Date of registration: | 22-Aug-2024 |
| Faculty: | M - Medizinische Fakultät |
| Department: | M - Physiologie |
| Professorship: | M - Prof. Dr. Frank Kirchhoff |
| Collections: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
Files for this record:
| File | Description | Size | Format | |
|---|---|---|---|---|
| fimmu-15-1425706.pdf | 4,99 MB | Adobe PDF | View/Open |
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