Impairments in resource allocation and executive control in children with ADHD

Abstract

Children diagnosed with attention-deficit hyperactivity disorder (ADHD) show pronounced alterations in cognitive tasks, such as a highly variable mode of responding. There is an ongoing debate about the key driving mechanisms of such alterations (e.g. specific inhibition or working memory (WM) impairments or general impairments in the allocation of energetic resources). The aim of this study was to disentangle such process-specific versus general limitations in cognitive and energetic mechanisms in children with ADHD compared to typically developed (TD) children based on the performance in a task-switching paradigm. This paradigm allows for both a common measurement and a later segregation of different executive sub-processes. Task-switching performance, including performance variability, of 26 children diagnosed with combined-type ADHD (8-13 years) was compared against the performance of 26 age-matched/IQ-matched TD children. Results revealed that compared to TD children, ADHD-diagnosed children showed alterations in performance variability during task switching, both in general (indicating disturbances in resource allocation) and conditionally on WM demands (indicating a specific WM deficit). Hence, our study provides diagnostically relevant new insights into performance impairments in children with ADHD compared to TD children. Importantly, it seems mandatory to include information on performance variability when trying to phenotype alterations in cognitive performance in ADHD.