Dokumenttyp | Erscheinungsjahr | Titel | Autoren | Herausgeber |
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article | 2024 | High Target Homology Does Not Guarantee Inhibition: Aminothiazoles Emerge as Inhibitors of Plasmodium falciparum | Johannsen, Sandra; Gierse, Robin M.; Krüger, Arne; Edwards, Rachel L.; Nanna, Vittoria; Fontana, Anna; Zhu, Di; Masini, Tiziana; de Carvalho, Lais Pessanha; Poizat, Mael; Kieftenbelt, Bart; Hodge, Dana M.; Alvarez, Sophie; Bunt, Daan; Lacour, Antoine; Shams, Atanaz; Meissner, Kamila Anna; de Souza, Edmarcia Elisa; Dröge, Melloney; van Vliet, Bernard; den Hartog, Jack; Hutter, Michael C.; Held, Jana; Odom John, Audrey R.; Wrenger, Carsten; Hirsch, Anna | |
article | 2023 | Exploring the Translational Gap of a Novel Class of Escherichia coli IspE Inhibitors | Ropponen, Henni-Karoliina; Diamanti, Eleonora; Johannsen, Sandra; Illarionov, Boris; Hamid, Rawia Abdulazeem Ahmed; Jaki, Miriam; Sass, Peter; Fischer, Markus; Haupenthal, Jörg; Hirsch, Anna | |
doctoralThesis | 2022 | Exploiting multiple hit-identification strategies to identify novel inhibitors of the anti-infective target DXPS | Johannsen, Sandra | |
article | 2022 | Discovery of novel drug-like antitubercular hits targeting the MEP pathway enzyme DXPS by strategic application of ligand-based virtual screening | Zhu, Di; Johannsen, Sandra; Masini, Tiziana; Simonin, Céline; Haupenthal, Jörg; Illarionov, Boris; Andreas, Anastasia; Awale, Mahendra; Gierse, Robin M.; van der Laan, Tridia; van der Vlag, Ramon; Nasti, Rita; Poizat, Mael; Buhler, Eric; Reiling, Norbert; Müller, Rolf; Fischer, Markus; Reymond, Jean-Louis; Hirsch, Anna K. H. | |
article | 2021 | Hit-optimization using target-directed dynamic combinatorial chemistry : development of inhibitors of the anti-infective target 1-deoxy-d-xylulose-5-phosphate synthase | Jumde, Ravindra P.; Guardigni, Melissa; Gierse, Robin M.; Alhayek, Alaa; Zhu, Di; Hamid, Zhoor; Johannsen, Sandra; Elgaher, Walid A. M.; Neusens, Philipp J.; Nehls, Christian; Haupenthal, Jörg; Reiling, Norbert; Hirsch, Anna K. H. | |