| Dokumenttyp | Erscheinungsjahr | Titel | Autoren | Herausgeber |
|---|
| article | 2023 | Significant impact of time-of-day variation on metformin pharmacokinetics | Türk, Denise; Scherer, Nina; Selzer, Dominik; Dings, Christiane; Hanke, Nina; Dallmann, Robert; Schwab, Matthias; Timmins, Peter; Nock, Valerie; Lehr, Thorsten | |
| article | 2021 | Pharmacokinetics of the CYP3A4 and CYP2B6 Inducer Carbamazepine and Its Drug–Drug Interaction Potential: A Physiologically Based Pharmacokinetic Modeling Approach | Fuhr, Laura Maria; Marok, Fatima Zahra; Hanke, Nina; Selzer, Dominik; Lehr, Thorsten | |
| article | 2021 | Physiologically Based Pharmacokinetic Modeling of Bupropion and Its Metabolites in a CYP2B6 Drug-Drug-Gene Interaction Network | Marok, Fatima Zahra; Fuhr, Laura Maria; Hanke, Nina; Selzer, Dominik; Lehr, Thorsten | |
| article | 2020 | Physiologically Based Pharmacokinetic Modeling of Metoprolol Enantiomers and α-Hydroxymetoprolol to Describe CYP2D6 Drug-Gene Interactions | Rüdesheim, Simeon; Wojtyniak, Jan-Georg; Selzer, Dominik; Hanke, Nina; Mahfoud, Felix; Schwab, Matthias; Lehr, Thorsten | |
| article | 2020 | A Physiologically-Based Pharmacokinetic Model of Trimethoprim for MATE1, OCT1, OCT2, and CYP2C8 Drug–Drug–Gene Interaction Predictions | Türk, Denise; Hanke, Nina; Lehr, Thorsten | |
| article | 2020 | A Mechanistic, Enantioselective, Physiologically Based Pharmacokinetic Model of Verapamil and Norverapamil, Built and Evaluated for Drug–Drug Interaction Studies | Hanke, Nina; Türk, Denise; Selzer, Dominik; Wiebe, Sabrina; Fernandez, Éric; Stopfer, Peter; Nock, Valerie; Lehr, Thorsten | |
| article | 2020 | Physiologically Based Pharmacokinetic Models of Probenecid and Furosemide to Predict Transporter Mediated Drug-Drug Interactions | Britz, Hannah; Hanke, Nina; Taub, Mitchell E.; Wang, Ting; Prasad, Bhagwat; Fernandez, Éric; Stopfer, Peter; Nock, Valerie; Lehr, Thorsten | |
| article | 2020 | Effective Removal of Dabigatran by Idarucizumab or Hemodialysis: A Physiologically Based Pharmacokinetic Modeling Analysis | Fuhr, Laura Maria; Hanke, Nina; Meibohm, Bernd; Lehr, Thorsten | |
| article | 2020 | A Comprehensive Whole-Body Physiologically Based Pharmacokinetic Drug-Drug-Gene Interaction Model of Metformin and Cimetidine in Healthy Adults and Renally Impaired Individuals | Hanke, Nina; Türk, Denise; Selzer, Dominik; Ishiguro, Naoki; Ebner, Thomas; Wiebe, Sabrina; Müller, Fabian; Stopfer, Peter; Nock, Valerie; Lehr, Thorsten | |
| article | 2019 | A Comprehensive Whole-Body Physiologically Based Pharmacokinetic Model of Dabigatran Etexilate, Dabigatran and Dabigatran Glucuronide in Healthy Adults and Renally Impaired Patients | Moj, Daniel; Maas, Hugo; Schaeftlein, André; Hanke, Nina; Gómez-Mantilla, José David; Lehr, Thorsten | |
| article | 2019 | Physiologically Based Pharmacokinetic Models for Prediction of Complex CYP2C8 and OATP1B1 (SLCO1B1) Drug-Drug-Gene Interactions : A Modeling Network of Gemfibrozil, Repaglinide, Pioglitazone, Rifampicin, Clarithromycin and Itraconazole | Türk, Denise; Hanke, Nina; Wolf, Sarah; Frechen, Sebastian; Eissing, Thomas; Wendl, Thomas; Schwab, Matthias; Lehr, Thorsten | |
| article | 2019 | Translational PBPK Modeling of the Protein Therapeutic and CD95L Inhibitor Asunercept to Develop Dose Recommendations for Its First Use in Pediatric Glioblastoma Patients | Hanke, Nina; Kunz, Claudia; Thiemann, Meinolf; Fricke, Harald; Lehr, Thorsten | |
| article | 2019 | Physiologically-Based Pharmacokinetic Models for CYP1A2 Drug-Drug Interaction Prediction: A Modeling Network of Fluvoxamine, Theophylline, Caffeine, Rifampicin, and Midazolam | Britz, Hannah; Hanke, Nina; Volz, Anke-Katrin; Spigset, Olav; Schwab, Matthias; Eissing, Thomas; Wendl, Thomas; Frechen, Sebastian; Lehr, Thorsten | |
| article | 2018 | PBPK Models for CYP3A4 and P-gp DDI Prediction: A Modeling Network of Rifampicin, Itraconazole, Clarithromycin, Midazolam, Alfentanil, and Digoxin | Hanke, Nina; Frechen, Sebastian; Moj, Daniel; Britz, Hannah; Eissing, Thomas; Wendl, Thomas; Lehr, Thorsten | |
| article | 2018 | Population nutrikinetics of green tea extract | Scholl, Catharina; Lepper, Anna; Lehr, Thorsten; Hanke, Nina; Schneider, Katharina Luise; Brockmöller, Jürgen; Seufferlein, Thomas; Stingl, Julia Carolin | |
| article | 2017 | A physiologically based pharmacokinetic (PBPK) parent-metabolite model of the chemotherapeutic zoptarelin doxorubicin-integration of in vitro results, Phase I and Phase II data and model application for drug-drug interaction potential analysis | Hanke, Nina; Teifel, Michael; Moj, Daniel; Wojtyniak, Jan-Georg; Britz, Hannah; Aicher, Babette; Sindermann, Herbert; Ammer, Nicola; Lehr, Thorsten | |
https://orcid.org/0000-0001-6166-8838