Dokumenttyp | Erscheinungsjahr | Titel | Autoren | Herausgeber |
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article | 2024 | Gene Editing and Small Molecule Inhibitors of the RNA Binding Protein IGF2BP2/IMP2 Show its Potential as an Anti-Cancer Drug Target | Chanda, Shilpee; Lepikhov, Konstantin; Dahlem, Charlotte; Schymik, Hanna S.; Hoppstädter, Jessica; Geber, An-Kristin; Wagner, Konrad; Kessler, Sonja M.; Empting, Martin; Kiemer, Alexandra | |
article | 2022 | Identification and Biochemical Characterization of Pyrrolidinediones as Novel Inhibitors of the Bacterial Enzyme MurA | Fathalla, Reem K.; Fröhner, Wolfgang; Bader, Chantal D.; Fischer, Patrick D.; Dahlem, Charlotte; Chatterjee, Deep; Mathea, Sebastian; Kiemer, Alexandra K.; Arthanari, Haribabu; Müller, Rolf; Abdel-Halim, Mohammad; Ducho, Christian; Engel, Matthias | |
article | 2022 | Induction of Liver Size Reduction in Zebrafish Larvae by the Emerging Synthetic Cannabinoid 4F-MDMB-BINACA and Its Impact on Drug Metabolism | Park, Yu Mi; Dahlem, Charlotte; Meyer, Markus R.; Kiemer, Alexandra K.; Müller, Rolf; Herrmann, Jennifer | |
article | 2022 | Characterization of Anti-Cancer Activities of Violacein: Actions on Tumor Cells and the Tumor Microenvironment | Dahlem, Charlotte; Chanda, Shilpee; Hemmer, Jan; Schymik, Hanna S.; Kohlstedt, Michael; Wittmann, Christoph; Kiemer, Alexandra K. | |
article | 2022 | Comment on: The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ | Schymik, Hanna S.; Dahlem, Charlotte; Barghash, Ahmad; Kiemer, Alexandra K. | |
article | 2022 | First Small-Molecule Inhibitors Targeting the RNA-Binding Protein IGF2BP2/IMP2 for Cancer Therapy | Dahlem, Charlotte; Abuhaliema, Ali; Kessler, Sonja M.; Kröhler, Tarek; Zoller, Ben G. E.; Chanda, Shilpee; Wu, Yingwen; Both, Simon; Müller, Fabian; Lepikhov, Konstantin; Kirsch, Susanne H.; Laggai, Stephan; Müller, Rolf; Empting, Martin; Kiemer, Alexandra K. | |
article | 2021 | Dysregulation of cholesterol homeostasis in human lung cancer tissue and tumour-associated macrophages | Hoppstädter, Jessica; Dembek, Anna; Höring, Marcus; Schymik, Hanna S.; Dahlem, Charlotte; Sultan, Afnan; Wirth, Natalie; Al-Fityan, Salma; Diesel, Britta; Gasparoni, Gilles; Walter, Jörn; Helms, Volkhard; Huwer, Hanno; Simon, Martin; Liebisch, Gerhard; Schulz, Marcel H.; Kiemer, Alexandra K. | |
article | 2020 | Baikalomycins A-C, New Aquayamycin-Type Angucyclines Isolated from Lake Baikal Derived Streptomyces sp. IB201691-2A | Voitsekhovskaia, Irina; Paulus, Constanze; Dahlem, Charlotte; Rebets, Yuriy; Nadmid, Suvd; Zapp, Josef; Axenov-Gribanov, Denis; Rückert, Christian; Timofeyev, Maxim; Kalinowski, Jörn; Kiemer, Alexandra K.; Luzhetskyy, Andriy | |
article | 2020 | The glucocorticoid-induced leucine zipper mediates statin-induced muscle damage | Hoppstädter, Jessica; Valbuena Perez, Jenny Vanessa; Linnenberger, Rebecca; Dahlem, Charlotte; Legroux, Thierry M.; Hecksteden, Anne; Tse, William K. F.; Flamini, Sara; Andreas, Anastasia; Herrmann, Jennifer; Herr, Christian; Müller, Rolf; Meyer, Tim; Bals, Robert; Riccardi, Carlo; Bruscoli, Stefano; Kiemer, Alexandra K. | |
article | 2020 | Myxobacteria-Derived Outer Membrane Vesicles: Potential Applicability Against Intracellular Infections | Goes, Adriely; Lapuhs, Philipp; Kuhn, Thomas; Schulz, Eilien; Richter, Robert; Panter, Fabian; Dahlem, Charlotte; Koch, Marcus; Garcia, Ronald; Kiemer, Alexandra K.; Müller, Rolf; Fuhrmann, Gregor | |
doctoralThesis | 2020 | In vitro and in vivo characterization of therapeutic approaches for solid tumors : natural compounds and novel targets | Dahlem, Charlotte | |
article | 2020 | Thioholgamide A, a New Anti-Proliferative Anti-Tumor Agent, Modulates Macrophage Polarization and Metabolism | Dahlem, Charlotte; Siow, Wei Xiong; Lopatniuk, Maria; Tse, William K. F.; Kessler, Sonja M.; Kirsch, Susanne H.; Hoppstädter, Jessica; Vollmar, Angelika M.; Müller, Rolf; Luzhetskyy, Andriy; Bartel, Karin; Kiemer, Alexandra K. | |
article | 2019 | The Insulin-Like Growth Factor 2 mRNA Binding Protein IMP2/IGF2BP2 is Overexpressed and Correlates with Poor Survival in Pancreatic Cancer | Dahlem, Charlotte; Barghash, Ahmad; Puchas, Philip; Haybaeck, Johannes; Kessler, Sonja M. | |
article | 2019 | Targeted delivery of functionalized PLGA nanoparticles to macrophages by complexation with the yeast Saccharomyces cerevisiae | Kiefer, Ruth; Jurisic, Marijas; Dahlem, Charlotte; Koch, Marcus; Schmitt, Manfred J.; Kiemer, Alexandra K.; Schneider, Marc; Breinig, Frank | |
article | 2019 | Toll-Like Receptor 2 Release by Macrophages: An Anti-inflammatory Program Induced by Glucocorticoids and Lipopolysaccharide | Hoppstädter, Jessica; Dembek, Anna; Linnenberger, Rebecca; Dahlem, Charlotte; Barghash, Ahmad; Fecher-Trost, Claudia; Fuhrmann, Gregor; Koch, Marcus; Kraegeloh, Annette; Huwer, Hanno; Kiemer, Alexandra | |
article | 2019 | Perquinolines A-C: Unprecedented Bacterial Tetrahydroisoquinolines Involving an Intriguing Biosynthesis | Rebets, Yuriy; Nadmid, Suvd; Paulus, Constanze; Dahlem, Charlotte; Herrmann, Jennifer; Hübner, Harald; Rückert, Christian; Kiemer, Alexandra K.; Gmeiner, Peter; Kalinowski, Jörn; Müller, Rolf; Luzhetskyy, Andriy | |