Please use this identifier to cite or link to this item: doi:10.22028/D291-47610
Title: Mediating roles of attention-deficit/hyperactivity disorder symptom severity and self-control on the relationship between adverse childhood experiences and adult aggression
Author(s): Merscher, Johannes
Retz, Wolfgang
Retz-Junginger, Petra
Barra, Steffen
Language: English
Title: Journal of Neural Transmission
Volume: 133 (2026)
Issue: 3
Pages: 561-575
Publisher/Platform: Springer Nature
Year of Publication: 2025
Free key words: ADHD
Self-control
Adverse childhood experiences
Aggression
DDC notations: 610 Medicine and health
Publikation type: Journal Article
Abstract: Previous research has identified attention-deficit/hyperactivity disorder (ADHD), adverse childhood experiences (ACEs), and low self-control as risk factors for aggressive behavior. While associations among these variables have been widely documented, the underlying mechanisms remain unclear. Grounded in the General Theory of Crime, this study investigates the relationship between ACEs and aggression, with a particular focus on the mediating roles of ADHD and self-control in a serial mediation model. Based on the theoretically grounded assumption that ACEs contribute to adult ADHD symp tomatology, which impairs self-control and predicts aggressive behavior, this study examines the dynamic interplay among these constructs in a mixed-gender sample of 350 participants aged 18 to 76 years (M = 34.9, SD = 13.1). Serial mediation analyses revealed positive associations between ACEs and aggression, as well as between ACEs and ADHD. Addition ally, a significant positive correlation was observed between ADHD and aggression. Conversely, self-control exhibited a negative relationship with both ADHD and aggression. Mediation analyses indicated that ADHD and self-control partially mediated the link between ACEs and aggression in adults irrespective of gender and age. Our results suggest that violence prevention efforts could benefit from early interventions aimed at reducing ACEs, diagnostic assessment and treatment of ADHD symptoms, and therapeutic interventions designed to enhance self-control and thereby mitigate their impact on aggression.
DOI of the first publication: 10.1007/s00702-025-03010-1
URL of the first publication: https://doi.org/10.1007/s00702-025-03010-1
Link to this record: urn:nbn:de:bsz:291--ds-476103
hdl:20.500.11880/41639
http://dx.doi.org/10.22028/D291-47610
ISSN: 1435-1463
0300-9564
Date of registration: 29-Apr-2026
Description of the related object: Supplementary Information
Related object: https://static-content.springer.com/esm/art%3A10.1007%2Fs00702-025-03010-1/MediaObjects/702_2025_3010_MOESM1_ESM.docx
Faculty: M - Medizinische Fakultät
Department: M - Forensische Psychologie und Psychiatrie
Professorship: M - Prof. Dr. Wolfgang Retz
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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