Please use this identifier to cite or link to this item: doi:10.22028/D291-43645
Title: Prolonged course of brain edema and neurological recovery in a translational model of decompressive craniectomy after closed head injury in mice
Author(s): Szczygielski, Jacek
Hubertus, Vanessa
Kruchten, Eduard
Müller, Andreas
Albrecht, Lisa Franziska
Schwerdtfeger, Karsten
Oertel, Joachim
Language: English
Title: Frontiers in neurology
Volume: 14
Publisher/Platform: Frontiers
Year of Publication: 2023
Free key words: mouse model
brain edema
decompressive craniectomy
traumatic brain injury
magnetic resonance imaging
closed head injury
DDC notations: 610 Medicine and health
Publikation type: Journal Article
Abstract: The use of decompressive craniectomy in traumatic brain injury (TBI) remains a matter of debate. According to the DECRA trial, craniectomy may have a negative impact on functional outcome, while the RescueICP trial revealed a positive effect of surgical decompression, which is evolving over time. This ambivalence of craniectomy has not been studied extensively in controlled laboratory experiments.
DOI of the first publication: 10.3389/fneur.2023.1308683
URL of the first publication: https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.1308683/full
Link to this record: urn:nbn:de:bsz:291--ds-436459
hdl:20.500.11880/39114
http://dx.doi.org/10.22028/D291-43645
ISSN: 1664-2295
Date of registration: 3-Dec-2024
Faculty: M - Medizinische Fakultät
Department: M - Neurochirurgie
M - Radiologie
Professorship: M - Prof. Dr. Arno Bücker
M - Prof. Dr. Joachim Oertel
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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