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doi:10.22028/D291-43645 | Title: | Prolonged course of brain edema and neurological recovery in a translational model of decompressive craniectomy after closed head injury in mice |
| Author(s): | Szczygielski, Jacek Hubertus, Vanessa Kruchten, Eduard Müller, Andreas Albrecht, Lisa Franziska Schwerdtfeger, Karsten Oertel, Joachim |
| Language: | English |
| Title: | Frontiers in neurology |
| Volume: | 14 |
| Publisher/Platform: | Frontiers |
| Year of Publication: | 2023 |
| Free key words: | mouse model brain edema decompressive craniectomy traumatic brain injury magnetic resonance imaging closed head injury |
| DDC notations: | 610 Medicine and health |
| Publikation type: | Journal Article |
| Abstract: | The use of decompressive craniectomy in traumatic brain injury (TBI) remains a matter of debate. According to the DECRA trial, craniectomy may have a negative impact on functional outcome, while the RescueICP trial revealed a positive effect of surgical decompression, which is evolving over time. This ambivalence of craniectomy has not been studied extensively in controlled laboratory experiments. |
| DOI of the first publication: | 10.3389/fneur.2023.1308683 |
| URL of the first publication: | https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.1308683/full |
| Link to this record: | urn:nbn:de:bsz:291--ds-436459 hdl:20.500.11880/39114 http://dx.doi.org/10.22028/D291-43645 |
| ISSN: | 1664-2295 |
| Date of registration: | 3-Dec-2024 |
| Faculty: | M - Medizinische Fakultät |
| Department: | M - Neurochirurgie M - Radiologie |
| Professorship: | M - Prof. Dr. Arno Bücker M - Prof. Dr. Joachim Oertel |
| Collections: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| fneur-14-1308683.pdf | 7,34 MB | Adobe PDF | View/Open |
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