Please use this identifier to cite or link to this item:
doi:10.22028/D291-39950
Title: | Total synthesis of Myxoprincomide, a secondary metabolite from Myxococcus xanthus |
Author(s): | Kohr, Michael Walt, Christine Dastbaz, Jan Müller, Rolf Kazmaier, Uli |
Language: | English |
Title: | Organic & Biomolecular Chemistry |
Volume: | 20 |
Issue: | 48 |
Pages: | 9609-9612 |
Publisher/Platform: | Royal Society of Chemistry |
Year of Publication: | 2022 |
DDC notations: | 500 Science |
Publikation type: | Journal Article |
Abstract: | Myxoprincomide, a secondary metabolite of the myxobacterium Myxococcus xanthus DK 1622, is synthesised for the first time. The central, unusual α-ketoamide is generated at the end of the synthesis to avoid side reactions during the synthesis of this rather reactive subunit. Nevertheless, the synthetic natural product is obtained as an isomeric mixture. Detailed analytical investigations show that the identical isomeric mixture is found in the isolated natural product. |
DOI of the first publication: | 10.1039/D2OB02021A |
URL of the first publication: | https://pubs.rsc.org/en/content/articlelanding/2022/OB/D2OB02021A |
Link to this record: | urn:nbn:de:bsz:291--ds-399509 hdl:20.500.11880/35946 http://dx.doi.org/10.22028/D291-39950 |
ISSN: | 1477-0539 1477-0520 |
Date of registration: | 12-Jun-2023 |
Description of the related object: | Electronic supplementary information |
Related object: | https://www.rsc.org/suppdata/d2/ob/d2ob02021a/d2ob02021a1.pdf https://www.rsc.org/suppdata/d2/ob/d2ob02021a/d2ob02021a2.zip |
Faculty: | NT - Naturwissenschaftlich- Technische Fakultät |
Department: | NT - Chemie NT - Pharmazie |
Professorship: | NT - Prof. Dr. Uli Kazmaier NT - Prof. Dr. Rolf Müller |
Collections: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
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d2ob02021a.pdf | 459,55 kB | Adobe PDF | View/Open |
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