Please use this identifier to cite or link to this item:
Volltext verfügbar? / Dokumentlieferung
doi:10.22028/D291-38919
Title: | Flowing droplet interface bilayers: A microfluidic tool to control droplet trajectories and to study mechanical properties of unsupported lipid bilayers |
Author(s): | Walter, Cornelia Seemann, Ralf Fleury, Jean-Baptiste |
Language: | English |
Title: | Biomicrofluidics |
Volume: | 14 |
Issue: | 4 |
Publisher/Platform: | AIP Publishing |
Year of Publication: | 2020 |
DDC notations: | 500 Science |
Publikation type: | Journal Article |
Abstract: | We introduce the concept of Flowing Droplet Interface Bilayers (FDIBs) that are made of two droplets maintained in contact due to the presence of an adhesive lipidic surfactant. This system is similar to a flowing dumbbell made of two droplets interconnected by a lipid bilayer and driven by an external flow. Interestingly, such a dumbbell does not show a straight flow trajectory, but it oscillates between the sidewalls while moving along the microchannel. The origin of this unusual motion is hydrodynamic interactions, as demonstrated by analytical calculations and micro particle image velocimentry (μPiV) measurements. The hydrodynamic motion appears to be highly sensitive to the mechanical properties of the lipid bilayer connecting the two droplets (FDIB). Thus, droplet trajectories can be controlled by tuning the lipid bilayer composition, which enables in turn investigating mechanical properties of free-standing lipid bilayers. |
DOI of the first publication: | 10.1063/5.0011489 |
URL of the first publication: | https://doi.org/10.1063/5.0011489 |
Link to this record: | urn:nbn:de:bsz:291--ds-389195 hdl:20.500.11880/35111 http://dx.doi.org/10.22028/D291-38919 |
ISSN: | 1932-1058 |
Date of registration: | 6-Feb-2023 |
Faculty: | NT - Naturwissenschaftlich- Technische Fakultät |
Department: | NT - Physik |
Professorship: | NT - Prof. Dr. Ralf Seemann |
Collections: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
Files for this record:
There are no files associated with this item.
Items in SciDok are protected by copyright, with all rights reserved, unless otherwise indicated.