Please use this identifier to cite or link to this item: doi:10.22028/D291-38877
Title: Increasing the reflection efficiency of the Sedaconda ACD-S by heating and cooling the anaesthetic reflector: a bench study using a test lung
Author(s): Meiser, Andreas
Meis, Pierre Louis Fernando
O'Gara, Brian
Volk, Thomas
Kermad, Azzeddine
Language: English
Title: Journal of Clinical Monitoring and Computing
Publisher/Platform: Springer Nature
Year of Publication: 2023
Free key words: AnaConDa-S
Inhaled sedation
Bench study
Isofurane
DDC notations: 610 Medicine and health
Publikation type: Journal Article
Abstract: Background As volatile anaesthetic gases contribute to global warming, improving the efciency of their delivery can reduce their environmental impact. This can be achieved by rebreathing from a circle system, but also by anaesthetic refection with an open intensive care ventilator. We investigated whether the efciency of such a refection system could be increased by warming the refector during inspiration and cooling it during expiration (thermocycling). Methods The Sedaconda-ACD-S (Sedana Medical, Danderyd, Sweden) was connected between an intensive care ventilator and a test lung. Liquid isofurane was infused into the device at 0.5, 1.0, 2.0 and 5.0 mL/h; ventilator settings were 500 mL tidal volume, 12 bpm, 21% oxygen. Isofurane concentrations were measured inside the test lung after equilibration. Thermocycling was achieved by heating the breathing gas in the inspiratory hose to 37 °C via a heated humidifer without water. Breathing gas expired from the test lung was cooled to 14 °C before reaching the ACD-S. In the test lung, body temperature pressure saturated conditions prevailed. Isofurane concentrations and refective efciency were compared between thermocycling and control conditions. Results With thermocycling higher isofurane concentrations in the test lung were measured for all infusion rates studied. Interpolation of data showed that for achieving 0.4 (0.6) Vol% isofurane, the infusion rate can be reduced from 1.2 to 0.7 (2.0 to 1.2) mL/h or else to 56% (58%) of control. Conclusion Thermocycling of the anaesthetic gas considerably increases the efciency of the anaesthetic refector and reduces anaesthetic consumption by almost half in a test lung model. Given that cooling can be miniaturized, this method carries a potential for further saving anaesthetics in clinical practice in the operating theatre as well as for inhaled sedation in the ICU.
DOI of the first publication: 10.1007/s10877-022-00967-2
URL of the first publication: https://link.springer.com/article/10.1007/s10877-022-00967-2
Link to this record: urn:nbn:de:bsz:291--ds-388774
hdl:20.500.11880/35076
http://dx.doi.org/10.22028/D291-38877
ISSN: 1573-2614
1387-1307
Date of registration: 1-Feb-2023
Faculty: M - Medizinische Fakultät
Department: M - Anästhesiologie
Professorship: M - Prof. Dr. Thomas Volk
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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