Please use this identifier to cite or link to this item:
doi:10.22028/D291-38321
Title: | Effects of cardiovascular single pill combinations compared with identical multi-pill therapies on healthcare cost and utilization in Germany |
Author(s): | Wilke, Thomas Weisser, Burkhard Predel, Hans-Georg Schmieder, Roland E. Wassmann, Sven Gillessen, Anton Blettenberg, Jörg Maywald, Ulf Randerath, Olaf Müller, Sabrina Böhm, Michael |
Language: | English |
Title: | Journal of Comparative Effectiveness Research |
Volume: | 11 |
Issue: | 6 |
Pages: | 411–422 |
Publisher/Platform: | Future Medicine |
Year of Publication: | 2022 |
Free key words: | cardiology/cardiovascular comparative effectiveness research real-world evidence |
DDC notations: | 610 Medicine and health |
Publikation type: | Journal Article |
Abstract: | Aim: This study assessed whether a single pill combination (SPC) is associated with lower direct healthcare costs. Materials & methods: Anonymized claims data of patients ≥18 years treated with drugs for cardiovascular (CV)-related diseases either as a single pill combination or multi-pill combination (followup to 1 year) were evaluated. After propensity score matching, 59,336 out of 1,369,840 patients were analyzed. Results: In all cohorts, patients receiving a single pill combination had a lower frequency of general practitioner and specialist visits. The patients also had a significantly lower ratio of all-cause hospitalization days and number of CV-related prescriptions as well as all-cause prescriptions (with one exception) compared with those receiving a multi-pill combination. Conclusion: Direct CV-related costs were significantly lower in four out of seven comparisons, with a trend toward lower costs in the other three comparisons. |
DOI of the first publication: | 10.2217/cer-2021-0197 |
URL of the first publication: | http://dx.doi.org/10.2217/cer-2021-0197 |
Link to this record: | urn:nbn:de:bsz:291--ds-383215 hdl:20.500.11880/34579 http://dx.doi.org/10.22028/D291-38321 |
ISSN: | 2042-6313 2042-6305 |
Date of registration: | 30-Nov-2022 |
Description of the related object: | Supplementary data |
Related object: | https://www.futuremedicine.com/doi/suppl/10.2217/cer-2021-0197/suppl_file/supplemental+figure+2.jpg https://www.futuremedicine.com/doi/suppl/10.2217/cer-2021-0197/suppl_file/supplemental+figure+3.jpg https://www.futuremedicine.com/doi/suppl/10.2217/cer-2021-0197/suppl_file/supplemental+table+1.docx https://www.futuremedicine.com/doi/suppl/10.2217/cer-2021-0197/suppl_file/supplemental+table+2.docx |
Faculty: | M - Medizinische Fakultät |
Department: | M - Innere Medizin |
Professorship: | M - Prof. Dr. Michael Böhm |
Collections: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
Files for this record:
File | Description | Size | Format | |
---|---|---|---|---|
cer-2021-0197.pdf | 1,07 MB | Adobe PDF | View/Open |
This item is licensed under a Creative Commons License