Please use this identifier to cite or link to this item:
doi:10.22028/D291-37559
Title: | Mechanismen des Proteinimports in das humane endoplasmatische Retikulum |
Author(s): | Zimmermann, Richard |
Language: | German |
Title: | BIOspektrum |
Volume: | 28 |
Issue: | 5 |
Publisher/Platform: | Springer Nature |
Year of Publication: | 2022 |
DDC notations: | 610 Medicine and health |
Publikation type: | Journal Article |
Abstract: | In human cells, one third of all polypeptides enter the secretory pathway at the ER. This process involves N-terminal signal peptides or internal transmembrane helices in the precursors and one hundred cytosolic and ER proteins, which facilitate their ER import or processing. In the past fifty years four pathways for targeting of precursors to the Sec61 channel plus various allosteric channel effectors and supporting or stand alone membrane protein insertases were characterized by the field. |
DOI of the first publication: | 10.1007/s12268-022-1797-3 |
URL of the first publication: | https://link.springer.com/article/10.1007/s12268-022-1797-3 |
Link to this record: | urn:nbn:de:bsz:291--ds-375590 hdl:20.500.11880/33981 http://dx.doi.org/10.22028/D291-37559 |
ISSN: | 1868-6249 0947-0867 |
Date of registration: | 12-Oct-2022 |
Faculty: | M - Medizinische Fakultät |
Department: | M - Medizinische Biochemie und Molekularbiologie |
Professorship: | M - Keiner Professur zugeordnet |
Collections: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
Files for this record:
File | Description | Size | Format | |
---|---|---|---|---|
s12268-022-1797-3.pdf | 604,44 kB | Adobe PDF | View/Open |
This item is licensed under a Creative Commons License