Please use this identifier to cite or link to this item: doi:10.22028/D291-37559
Title: Mechanismen des Proteinimports in das humane endoplasmatische Retikulum
Author(s): Zimmermann, Richard
Language: German
Title: BIOspektrum
Volume: 28
Issue: 5
Publisher/Platform: Springer Nature
Year of Publication: 2022
DDC notations: 610 Medicine and health
Publikation type: Journal Article
Abstract: In human cells, one third of all polypeptides enter the secretory pathway at the ER. This process involves N-terminal signal peptides or internal transmembrane helices in the precursors and one hundred cytosolic and ER proteins, which facilitate their ER import or processing. In the past fifty years four pathways for targeting of precursors to the Sec61 channel plus various allosteric channel effectors and supporting or stand alone membrane protein insertases were characterized by the field.
DOI of the first publication: 10.1007/s12268-022-1797-3
URL of the first publication:
Link to this record: urn:nbn:de:bsz:291--ds-375590
ISSN: 1868-6249
Date of registration: 12-Oct-2022
Faculty: M - Medizinische Fakultät
Department: M - Medizinische Biochemie und Molekularbiologie
Professorship: M - Keiner Professur zugeordnet
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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