Please use this identifier to cite or link to this item:
doi:10.22028/D291-37439
Title: | Comment on: The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ |
Author(s): | Schymik, Hanna S. Dahlem, Charlotte Barghash, Ahmad Kiemer, Alexandra K. |
Language: | English |
Title: | Advanced Science |
Volume: | 9 |
Issue: | 8 |
Publisher/Platform: | Wiley |
Year of Publication: | 2022 |
Free key words: | human macrophages IFNγ Ι IGF2BP2 LPS macrophage polarization mouse macrophages species difference |
DDC notations: | 500 Science |
Publikation type: | Journal Article |
Abstract: | Recently, first insights into the regulation and the role of the RNA-binding protein IMP2 in macrophage activation have been published by Wang et al. This study addresses differences in the regulation of IMP2 between the human and murine system. While the expression of IMP2 in anti-inflammatory macrophages is synchronous in mice and men, IMP2 expression is regulated differently in inflammatory macrophages. |
DOI of the first publication: | 10.1002/advs.202104372 |
URL of the first publication: | https://onlinelibrary.wiley.com/doi/10.1002/advs.202104372 |
Link to this record: | urn:nbn:de:bsz:291--ds-374397 hdl:20.500.11880/33862 http://dx.doi.org/10.22028/D291-37439 |
ISSN: | 2198-3844 |
Date of registration: | 29-Sep-2022 |
Description of the related object: | Supporting Information |
Faculty: | NT - Naturwissenschaftlich- Technische Fakultät |
Department: | NT - Pharmazie |
Professorship: | NT - Prof. Dr. Alexandra K. Kiemer |
Collections: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
Files for this record:
File | Description | Size | Format | |
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Advanced Science - 2022 - Schymik - Comment on The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and.pdf | 1,03 MB | Adobe PDF | View/Open |
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