Please use this identifier to cite or link to this item: doi:10.22028/D291-37439
Title: Comment on: The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ
Author(s): Schymik, Hanna S.
Dahlem, Charlotte
Barghash, Ahmad
Kiemer, Alexandra K.
Language: English
Title: Advanced Science
Volume: 9
Issue: 8
Publisher/Platform: Wiley
Year of Publication: 2022
Free key words: human macrophages
IFNγ Ι IGF2BP2
LPS
macrophage polarization
mouse macrophages
species difference
DDC notations: 500 Science
Publikation type: Journal Article
Abstract: Recently, first insights into the regulation and the role of the RNA-binding protein IMP2 in macrophage activation have been published by Wang et al. This study addresses differences in the regulation of IMP2 between the human and murine system. While the expression of IMP2 in anti-inflammatory macrophages is synchronous in mice and men, IMP2 expression is regulated differently in inflammatory macrophages.
DOI of the first publication: 10.1002/advs.202104372
URL of the first publication: https://onlinelibrary.wiley.com/doi/10.1002/advs.202104372
Link to this record: urn:nbn:de:bsz:291--ds-374397
hdl:20.500.11880/33862
http://dx.doi.org/10.22028/D291-37439
ISSN: 2198-3844
Date of registration: 29-Sep-2022
Description of the related object: Supporting Information
Faculty: NT - Naturwissenschaftlich- Technische Fakultät
Department: NT - Pharmazie
Professorship: NT - Prof. Dr. Alexandra K. Kiemer
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes



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