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doi:10.22028/D291-36032
Titel: | Insertion site of central venous catheter correlates with catheter-related infectious events in patients undergoing intensive chemotherapy |
VerfasserIn: | Rixecker, Torben Lesan, Vadim Ahlgrimm, Manfred Thurner, Lorenz Bewarder, Moritz Murawski, Niels Christofyllakis, Konstantinos Altmeyer, Sarah Bick, Angelika Stilgenbauer, Stephan Bittenbring, Joerg Thomas Kaddu-Mulindwa, Dominic |
Sprache: | Englisch |
Titel: | Bone Marrow Transplantation |
Bandnummer: | 56 |
Heft: | 1 |
Seiten: | 195–201 |
Verlag/Plattform: | Springer Nature |
Erscheinungsjahr: | 2020 |
Dokumenttyp: | Journalartikel / Zeitschriftenartikel |
Abstract: | Patients undergoing intensive chemotherapy are usually in need for central venous catheters (CVC). Due to contradictory study results, relation of insertion site and CVC-associated complication rate in these patients is not clear. We therefore retrospectively analyzed CVC-related data of all patients undergoing intensive chemotherapy with high risk of febrile neutropenia according to NCCN criteria, who received a CVC at our bone marrow transplantation unit between May 2016 and December 2019. In total, 210 patients received 281 CVC. CVC were placed via either the subclavian-vein (SCV, n = 58; 20%) or the internal-jugular-vein (IJV, n = 223; 80%). Median duration of CVC-lifetime and neutropenic days per CVC were comparable between the two groups (IJV vs SCV: 23 days vs 21 days (p = 0.16) and 12 days vs 11 days (p = 0.65)). Both, time to CVC removal due to local inflammation and time to central line-associated bloodstream infection was significantly shorter in patients with SCV catheters (p = 0.013 and p = 0.045). CVC placed in the IJV were associated with significantly less catheter-related infectious events compared with CVC placed in the SCV. This difference was consistent across different subgroups including 88 patients undergoing allogeneic stem cell transplantation. |
DOI der Erstveröffentlichung: | 10.1038/s41409-020-01003-0 |
URL der Erstveröffentlichung: | https://www.nature.com/articles/s41409-020-01003-0 |
Link zu diesem Datensatz: | hdl:20.500.11880/32828 http://dx.doi.org/10.22028/D291-36032 |
ISSN: | 1476-5365 0268-3369 |
Datum des Eintrags: | 21-Apr-2022 |
Fakultät: | M - Medizinische Fakultät |
Fachrichtung: | M - Innere Medizin |
Professur: | M - Prof. Dr. Stephan Stilgenbauer M - Dr. med. Lorenz Thurner |
Sammlung: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
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