Please use this identifier to cite or link to this item:
doi:10.22028/D291-35837
Title: | Long-Term Follow-Up of Survivors of Extracorporeal Life Support Therapy for Cardiogenic Shock: Are They Really Survivors? |
Author(s): | Berger, Rafal Nemeth, Attila Sandoval Boburg, Rodrigo Vöhringer, Louise Lausberg, Henning Florian Acharya, Metesh Schlensak, Christian Popov, Aron-Frederik |
Language: | English |
Title: | Medicina |
Volume: | 58 |
Issue: | 3 |
Publisher/Platform: | MDPI |
Year of Publication: | 2022 |
Free key words: | cardiogenic shock extracorporeal membrane oxygenation long-term follow-up |
DDC notations: | 610 Medicine and health |
Publikation type: | Journal Article |
Abstract: | Background and Objectives: Cardiogenic shock (CS) is a medical emergency associated with a high mortality rate. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has become an accepted therapy for CS. Despite widely available data for short-term survival rates, there are only limited data available regarding long-term outcomes following successful VA-ECMO therapy. Materials and Methods: We analyzed the demographics, past medical history, adverse events, and outcomes of survivors who received VA-ECMO support for CS at our center from January 2012 to December 2019. Post-cardiotomy cases were excluded. Results: A total of 578 VA-ECMO implantations on 564 consecutive patients due to CS were identified during the study period. Successful weaning was achieved in 207 (36.7%) patients. Among the survivors, 126 (63%) patients received VA-ECMO therapy without preceding cardiac surgery during their current admission. A follow-up exceeding 12 (mean: 36 ± 20.9) months was available in a total of 55 (43.7%) survivors. The mean VA-ECMO perfusion time was 10.9 (±7.7) days with a mean intensive care unit (ICU) stay of 38.2 (±29.9) days and a mean hospital stay of 49.9 (±30.5) days. A total of 3 deaths were recorded during long-term follow-up (mean survival of 26 ± 5.3 months). Conclusions: Despite the high mortality associated with VA-ECMO therapy, a long-term follow-up with an acceptably low rate of negative cardiac events can be achieved in many survivors. We observed an acceptable low rate of new cardiac events. Further evaluation, including a quality-of-life assessment and a close follow-up for rarer complications in these patients, is needed to elucidate the longer-term outcomes for survivors of invasive VA-ECMO therapy. |
DOI of the first publication: | 10.3390/medicina58030427 |
Link to this record: | urn:nbn:de:bsz:291--ds-358373 hdl:20.500.11880/32683 http://dx.doi.org/10.22028/D291-35837 |
ISSN: | 1648-9144 |
Date of registration: | 29-Mar-2022 |
Faculty: | M - Medizinische Fakultät |
Department: | M - Chirurgie |
Professorship: | M - Keiner Professur zugeordnet |
Collections: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
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