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doi:10.22028/D291-34404 | Title: | Evaluating the Use of Circulating MicroRNA Profiles for Lung Cancer Detection in Symptomatic Patients |
| Author(s): | Fehlmann, Tobias Kahraman, Mustafa Ludwig, Nicole Backes, Christina Galata, Valentina Keller, Verena Geffers, Lars Mercaldo, Nathaniel Hornung, Daniela Weis, Tanja Kayvanpour, Elham Abu-Halima, Masood Deuschle, Christian Schulte, Claudia Suenkel, Ulrike von Thaler, Anna-Katharina Maetzler, Walter Herr, Christian Fähndrich, Sebastian Vogelmeier, Claus Guimaraes, Pedro Hecksteden, Anne Meyer, Tim Metzger, Florian Diener, Caroline Deutscher, Stephanie Abdul-Khaliq, Hashim Stehle, Ingo Haeusler, Sebastian Meiser, Andreas Groesdonk, Heinrich V Volk, Thomas Lenhof, Hans-Peter Katus, Hugo Balling, Rudi Meder, Benjamin Kruger, Rejko Huwer, Hanno Bals, Robert Meese, Eckart Keller, Andreas |
| Language: | English |
| Title: | JAMA oncology |
| Volume: | 6 |
| Issue: | 5 |
| Startpage: | 714 |
| Endpage: | 723 |
| Publisher/Platform: | American Medical Association |
| Year of Publication: | 2020 |
| Publikation type: | Journal Article |
| Abstract: | The overall low survival rate of patients with lung cancer calls for improved detection tools to enable better treatment options and improved patient outcomes. Multivariable molecular signatures, such as blood-borne microRNA (miRNA) signatures, may have high rates of sensitivity and specificity but require additional studies with large cohorts and standardized measurements to confirm the generalizability of miRNA signatures. |
| DOI of the first publication: | 10.1001/jamaoncol.2020.0001 |
| URL of the first publication: | https://jamanetwork.com/journals/jamaoncology/article-abstract/2761984 |
| Link to this record: | hdl:20.500.11880/31527 http://dx.doi.org/10.22028/D291-34404 |
| ISSN: | 2374-2445 2374-2437 |
| Date of registration: | 15-Jul-2021 |
| Faculty: | M - Medizinische Fakultät MI - Fakultät für Mathematik und Informatik |
| Department: | M - Anästhesiologie M - Medizinische Biometrie, Epidemiologie und medizinische Informatik MI - Informatik |
| Professorship: | M - Prof. Dr. Thomas Volk MI - Prof. Dr. Hans-Peter Lenhof |
| Collections: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
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