Please use this identifier to cite or link to this item:
doi:10.22028/D291-33451
Title: | Vegan Diet and Bone Health—Results from the Cross-Sectional RBVD Study |
Author(s): | Menzel, Juliane Abraham, Klaus Stangl, Gabriele I. Ueland, Per Magne Obeid, Rima Schulze, Matthias B. Herter-Aeberli, Isabelle Schwerdtle, Tanja Weikert, Cornelia |
Language: | English |
Title: | Nutrients |
Volume: | 13 |
Issue: | 2 |
Publisher/Platform: | MDPI |
Year of Publication: | 2021 |
Free key words: | bone health BUA SOS QUS vegan diet biomarker reduced rank regression RRR |
DDC notations: | 610 Medicine and health |
Publikation type: | Journal Article |
Abstract: | Scientific evidence suggests that a vegan diet might be associated with impaired bone health. Therefore, a cross-sectional study (n = 36 vegans, n = 36 omnivores) was used to investigate the associations of veganism with calcaneal quantitative ultrasound (QUS) measurements, along with the investigation of differences in the concentrations of nutrition- and bone-related biomarkers between vegans and omnivores. This study revealed lower levels in the QUS parameters in vegans compared to omnivores, e.g., broadband ultrasound attenuation (vegans: 111.8 ± 10.7 dB/MHz, omnivores: 118.0 ± 10.8 dB/MHz, p = 0.02). Vegans had lower levels of vitamin A, B2, lysine, zinc, selenoprotein P, n-3 fatty acids, urinary iodine, and calcium levels, while the concentrations of vitamin K1, folate, and glutamine were higher in vegans compared to omnivores. Applying a reduced rank regression, 12 out of the 28 biomarkers were identified to contribute most to bone health, i.e., lysine, urinary iodine, thyroid-stimulating hormone, selenoprotein P, vitamin A, leucine, α-klotho, n-3 fatty acids, urinary calcium/magnesium, vitamin B6, and FGF23. All QUS parameters increased across the tertiles of the pattern score. The study provides evidence of lower bone health in vegans compared to omnivores, additionally revealing a combination of nutrition-related biomarkers, which may contribute to bone health. Further studies are needed to confirm these findings. |
DOI of the first publication: | 10.3390/nu13020685 |
Link to this record: | urn:nbn:de:bsz:291--ds-334515 hdl:20.500.11880/30758 http://dx.doi.org/10.22028/D291-33451 |
ISSN: | 2072-6643 |
Date of registration: | 1-Mar-2021 |
Description of the related object: | Supplementary Materials |
Related object: | https://www.mdpi.com/2072-6643/13/2/685/s1 |
Faculty: | M - Medizinische Fakultät |
Department: | M - Innere Medizin |
Professorship: | M - Keiner Professur zugeordnet |
Collections: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
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File | Description | Size | Format | |
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nutrients-13-00685.pdf | 490,91 kB | Adobe PDF | View/Open |
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