Please use this identifier to cite or link to this item: doi:10.22028/D291-33451
Title: Vegan Diet and Bone Health—Results from the Cross-Sectional RBVD Study
Author(s): Menzel, Juliane
Abraham, Klaus
Stangl, Gabriele I.
Ueland, Per Magne
Obeid, Rima
Schulze, Matthias B.
Herter-Aeberli, Isabelle
Schwerdtle, Tanja
Weikert, Cornelia
Language: English
Title: Nutrients
Volume: 13
Issue: 2
Publisher/Platform: MDPI
Year of Publication: 2021
Free key words: bone health
reduced rank regression
DDC notations: 610 Medicine and health
Publikation type: Journal Article
Abstract: Scientific evidence suggests that a vegan diet might be associated with impaired bone health. Therefore, a cross-sectional study (n = 36 vegans, n = 36 omnivores) was used to investigate the associations of veganism with calcaneal quantitative ultrasound (QUS) measurements, along with the investigation of differences in the concentrations of nutrition- and bone-related biomarkers between vegans and omnivores. This study revealed lower levels in the QUS parameters in vegans compared to omnivores, e.g., broadband ultrasound attenuation (vegans: 111.8 ± 10.7 dB/MHz, omnivores: 118.0 ± 10.8 dB/MHz, p = 0.02). Vegans had lower levels of vitamin A, B2, lysine, zinc, selenoprotein P, n-3 fatty acids, urinary iodine, and calcium levels, while the concentrations of vitamin K1, folate, and glutamine were higher in vegans compared to omnivores. Applying a reduced rank regression, 12 out of the 28 biomarkers were identified to contribute most to bone health, i.e., lysine, urinary iodine, thyroid-stimulating hormone, selenoprotein P, vitamin A, leucine, α-klotho, n-3 fatty acids, urinary calcium/magnesium, vitamin B6, and FGF23. All QUS parameters increased across the tertiles of the pattern score. The study provides evidence of lower bone health in vegans compared to omnivores, additionally revealing a combination of nutrition-related biomarkers, which may contribute to bone health. Further studies are needed to confirm these findings.
DOI of the first publication: 10.3390/nu13020685
Link to this record: urn:nbn:de:bsz:291--ds-334515
ISSN: 2072-6643
Date of registration: 1-Mar-2021
Description of the related object: Supplementary Materials
Related object:
Faculty: M - Medizinische Fakultät
Department: M - Innere Medizin
Professorship: M - Keiner Professur zugeordnet
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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