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doi:10.22028/D291-31041 | Title: | H(O)TA: estimation of DNA methylation and hydroxylation levels and efficiencies from time course data |
| Author(s): | Kyriakopoulos, Charalampos Giehr, Peter Pascal Wolf, Verena |
| Language: | English |
| Title: | Bioinformatics |
| Volume: | 33 |
| Issue: | 11 |
| Startpage: | 1733 |
| Endpage: | 1734 |
| Publisher/Platform: | Oxford University Press |
| Year of Publication: | 2017 |
| Publikation type: | Journal Article |
| Abstract: | Methylation and hydroxylation of cytosines to form 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) belong to the most important epigenetic modifications and their vital role in the regulation of gene expression has been widely recognized. Recent experimental techniques allow to infer methylation and hydroxylation levels at CpG dinucleotides but require a sophisticated statistical analysis to achieve accurate estimates. |
| DOI of the first publication: | 10.1093/bioinformatics/btx042 |
| URL of the first publication: | https://academic.oup.com/bioinformatics/article/33/11/1733/2959907 |
| Link to this record: | hdl:20.500.11880/29192 http://dx.doi.org/10.22028/D291-31041 |
| ISSN: | 1460-2059 1367-4811 |
| Date of registration: | 28-May-2020 |
| Faculty: | MI - Fakultät für Mathematik und Informatik |
| Department: | MI - Informatik |
| Professorship: | MI - Prof. Dr. Verena Wolf |
| Collections: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
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