Please use this identifier to cite or link to this item: doi:10.22028/D291-31041
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Title: H(O)TA: estimation of DNA methylation and hydroxylation levels and efficiencies from time course data
Author(s): Kyriakopoulos, Charalampos
Giehr, Peter Pascal
Wolf, Verena
Language: English
Title: Bioinformatics
Volume: 33
Issue: 11
Startpage: 1733
Endpage: 1734
Publisher/Platform: Oxford University Press
Year of Publication: 2017
Publikation type: Journal Article
Abstract: Methylation and hydroxylation of cytosines to form 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) belong to the most important epigenetic modifications and their vital role in the regulation of gene expression has been widely recognized. Recent experimental techniques allow to infer methylation and hydroxylation levels at CpG dinucleotides but require a sophisticated statistical analysis to achieve accurate estimates.
DOI of the first publication: 10.1093/bioinformatics/btx042
URL of the first publication:
Link to this record: hdl:20.500.11880/29192
ISSN: 1460-2059
Date of registration: 28-May-2020
Faculty: MI - Fakultät für Mathematik und Informatik
Department: MI - Informatik
Professorship: MI - Prof. Dr. Verena Wolf
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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