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doi:10.22028/D291-29525 | Title: | A comprehensive analysis of 195 DNA methylomes reveals shared and cell-specific features of partially methylated domains |
| Author(s): | Salhab, Abdulrahman Nordström, Karl Gasparoni, Gilles Kattler, Kathrin Ebert, Peter Ramirez, Fidel Arrigoni, Laura Müller, Fabian Polansky, Julia K. Cadenas, Cristina Hengstler, Jan G. Lengauer, Thomas Manke, Thomas Walter, Jörn Erik |
| Language: | English |
| Title: | Genome biology |
| Volume: | 19 |
| Issue: | 1 |
| Publisher/Platform: | BioMed Central |
| Year of Publication: | 2018 |
| Publikation type: | Journal Article |
| Abstract: | Partially methylated domains are extended regions in the genome exhibiting a reduced average DNA methylation level. They cover gene-poor and transcriptionally inactive regions and tend to be heterochromatic. We present a comprehensive comparative analysis of partially methylated domains in human and mouse cells, to identify structural and functional features associated with them. |
| DOI of the first publication: | 10.1186/s13059-018-1510-5 |
| Link to this record: | hdl:20.500.11880/27913 http://dx.doi.org/10.22028/D291-29525 |
| ISSN: | 1465-6914 1474-760X 1465-6906 |
| Date of registration: | 26-Sep-2019 |
| Faculty: | NT - Naturwissenschaftlich- Technische Fakultät |
| Department: | NT - Biowissenschaften |
| Professorship: | NT - Prof. Dr. Jörn Walter |
| Collections: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
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