Please use this identifier to cite or link to this item: doi:10.22028/D291-29525
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Title: A comprehensive analysis of 195 DNA methylomes reveals shared and cell-specific features of partially methylated domains
Author(s): Salhab, Abdulrahman
Nordström, Karl
Gasparoni, Gilles
Kattler, Kathrin
Ebert, Peter
Ramirez, Fidel
Arrigoni, Laura
Müller, Fabian
Polansky, Julia K.
Cadenas, Cristina
Hengstler, Jan G.
Lengauer, Thomas
Manke, Thomas
Walter, Jörn Erik
Language: English
Title: Genome biology
Volume: 19
Issue: 1
Publisher/Platform: BioMed Central
Year of Publication: 2018
Publikation type: Journal Article
Abstract: Partially methylated domains are extended regions in the genome exhibiting a reduced average DNA methylation level. They cover gene-poor and transcriptionally inactive regions and tend to be heterochromatic. We present a comprehensive comparative analysis of partially methylated domains in human and mouse cells, to identify structural and functional features associated with them.
DOI of the first publication: 10.1186/s13059-018-1510-5
Link to this record: hdl:20.500.11880/27913
ISSN: 1465-6914
Date of registration: 26-Sep-2019
Faculty: NT - Naturwissenschaftlich- Technische Fakultät
Department: NT - Biowissenschaften
Professorship: NT - Prof. Dr. Jörn Walter
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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