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doi:10.22028/D291-29438
Title: | Histone and DNA methylation control by H3 serine 10/threonine 11 phosphorylation in the mouse zygote |
Author(s): | Lan, Jie Lepikhov, Konstantin Giehr, Peter Pascal Walter, Jörn Erik |
Language: | English |
Title: | Epigenetics & chromatin |
Volume: | 10 |
Issue: | 1 |
Startpage: | 1 |
Endpage: | 19 |
Publisher/Platform: | BioMed Central |
Year of Publication: | 2017 |
Publikation type: | Journal Article |
Abstract: | In the mammalian zygote, epigenetic reprogramming is a tightly controlled process of coordinated alterations of histone and DNA modifications. The parental genomes of the zygote show distinct patterns of histone H3 variants and distinct patterns of DNA and histone modifications. The molecular mechanisms linking histone variant-specific modifications and DNA methylation reprogramming during the first cell cycle remain to be clarified. |
DOI of the first publication: | 10.1186/s13072-017-0112-x |
URL of the first publication: | https://epigeneticsandchromatin.biomedcentral.com/articles/10.1186/s13072-017-0112-x |
Link to this record: | hdl:20.500.11880/27894 http://dx.doi.org/10.22028/D291-29438 |
ISSN: | 1756-8935 |
Date of registration: | 25-Sep-2019 |
Faculty: | NT - Naturwissenschaftlich- Technische Fakultät |
Department: | NT - Biowissenschaften |
Professorship: | NT - Prof. Dr. Jörn Walter |
Collections: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
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