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doi:10.22028/D291-28702
Title: | Bit-parallel sequence-to-graph alignment |
Author(s): | Rautiainen, Mikko Mäkinen, Veli Marschall, Tobias |
Language: | English |
Title: | Bioinformatics |
Publisher/Platform: | Oxford University Press |
Year of Publication: | 2019 |
Publikation type: | Journal Article |
Abstract: | Graphs are commonly used to represent sets of sequences. Either edges or nodes can be labeled by sequences, so that each path in the graph spells a concatenated sequence. Examples include graphs to represent genome assemblies, such as string graphs and de Bruijn graphs, and graphs to represent a pan-genome and hence the genetic variation present in a population. Being able to align sequencing reads to such graphs is a key step for many analyses and its applications include genome assembly, read error correction, and variant calling with respect to a variation graph. |
DOI of the first publication: | 10.1093/bioinformatics/btz162 |
Link to this record: | hdl:20.500.11880/27705 http://dx.doi.org/10.22028/D291-28702 |
ISSN: | 1367-4803 1460-2059 |
Date of registration: | 7-Sep-2019 |
Faculty: | MI - Fakultät für Mathematik und Informatik |
Department: | MI - Informatik |
Professorship: | MI - Prof. Dr. Tobias Marschall |
Collections: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
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