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|Title:||Bit-parallel sequence-to-graph alignment|
|Publisher/Platform:||Oxford University Press|
|Year of Publication:||2019|
|Publikation type:||Journal Article|
|Abstract:||Graphs are commonly used to represent sets of sequences. Either edges or nodes can be labeled by sequences, so that each path in the graph spells a concatenated sequence. Examples include graphs to represent genome assemblies, such as string graphs and de Bruijn graphs, and graphs to represent a pan-genome and hence the genetic variation present in a population. Being able to align sequencing reads to such graphs is a key step for many analyses and its applications include genome assembly, read error correction, and variant calling with respect to a variation graph.|
|DOI of the first publication:||10.1093/bioinformatics/btz162|
|Link to this record:||hdl:20.500.11880/27705|
|Date of registration:||7-Sep-2019|
|Faculty:||MI - Fakultät für Mathematik und Informatik|
|Department:||MI - Informatik|
|Professorship:||MI - Prof. Dr. Tobias Marschall|
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