| Dokumenttyp | Erscheinungsjahr | Titel | Autoren | Herausgeber |
|---|
| article | 2024 | Development and evaluation of 2,4-disubstituted-5-aryl pyrimidine derivatives as antibacterial agents | Khalifa, Hend; Rasheed, Sari Shawki; Haupenthal, Jörg; Herrmann, Jennifer; Mandour, Yasmine M.; Abadi, Ashraf H.; Engel, Matthias; Müller, Rolf; Hirsch, Anna; Abdel-Halim, Mohammad; Hamed, Mostafa M. | |
| article | 2024 | Synthesis and evaluation of novel N1-acylated 5-(4-pyridinyl)indazole derivatives as potent and selective haspin inhibitors | Shawky, Mona M.; Abdallah, Mennatallah; Khalifa, Hend; Aboushady, Youssef; Abadi, Ashraf H.; Engel, Matthias; Abdel-Halim, Mohammad | |
| article | 2024 | N-Benzylated 5-Hydroxybenzothiophene-2-carboxamides as Multi-Targeted Clk/Dyrk Inhibitors and Potential Anticancer Agents | Mostafa, Noha; Chen, Po-Jen; Darwish, Sarah S.; Su, Yu-Chieh; Shiao, Ming-Hua; Piazza, Gary A.; Abadi, Ashraf H.; Engel, Matthias; Abdel-Halim, Mohammad | |
| article | 2024 | N1-Benzoylated 5-(4-pyridinyl)indazole-based kinase inhibitors: Attaining haspin and Clk4 selectivity via modulation of the benzoyl substituents | Aboelfotouh, Habiba G.; Abdallah, Mennatallah; Khalifa, Hend; Aboushady, Youssef; Abadi, Ashraf H.; Engel, Matthias; Abdel-Halim, Mohammad | |
| article | 2023 | Targeting the binding pocket of the fluorophore 8-anilinonaphthalene-1-sulfonic acid in the bacterial enzyme MurA | Fathalla, Reem K.; Engel, Matthias; Ducho, Christian | |
| article | 2022 | Identification and Biochemical Characterization of Pyrrolidinediones as Novel Inhibitors of the Bacterial Enzyme MurA | Fathalla, Reem K.; Fröhner, Wolfgang; Bader, Chantal D.; Fischer, Patrick D.; Dahlem, Charlotte; Chatterjee, Deep; Mathea, Sebastian; Kiemer, Alexandra K.; Arthanari, Haribabu; Müller, Rolf; Abdel-Halim, Mohammad; Ducho, Christian; Engel, Matthias | |
| article | 2022 | Development of (4-Phenylamino)quinazoline Alkylthiourea Derivatives as Novel NF-κB Inhibitors | Darwish, Sarah S.; Chen, Po-Jen; Hamed, Mostafa M.; Wagdy, Reem A.; Chen, Shun-Hua; Abadi, Ashraf H.; Abdel-Halim, Mohammad; Hwang, Tsong-Long; Engel, Matthias | |
| article | 2022 | Nanoparticle Fraught Liposomes : A Platform for Increased Antibiotic Selectivity in Multidrug Resistant Bacteria | Fangary, Suzan; Abdel-Halim, Mohammad; Fathalla, Reem K.; Hassan, Raghda; Farag, Noha; Engel, Matthias; Mansour, Samar; Tammam, Salma N. | |
| article | 2022 | Development of novel conformationally restricted selective Clk1/4 inhibitors through creating an intramolecular hydrogen bond involving an imide linker | El-Gamil, Dalia S.; ElHady, Ahmed K.; Chen, Po-Jen; Hwang, Tsong-Long; Abadi, Ashraf H.; Abdel-Halim, Mohammad; Engel, Matthias | |
| article | 2021 | 5-Methoxybenzothiophene-2-Carboxamides as Inhibitors of Clk1/4: Optimization of Selectivity and Cellular Potency | ElHady, Ahmed K.; El-Gamil, Dalia S.; Chen, Po-Jen; Hwang, Tsong-Long; Abadi, Ashraf H.; Abdel-Halim, Mohammad; Engel, Matthias | |
| article | 2021 | Discovery of Hydroxybenzothiazole Urea Compounds as Multitargeted Agents Suppressing Major Cytotoxic Mechanisms in Neurodegenerative Diseases | Aboushady, Youssef; Gabr, Moustafa; ElHady, Ahmed K.; Salah, Mohamed; Abadi, Ashraf H.; Wilms, Gerrit; Becker, Walter; Abdel-Halim, Mohammad; Engel, Matthias | |
| article | 2020 | Discovery of trisubstituted pyrazolines as a novel scaffold for the development of selective phosphodiesterase 5 inhibitors | Abdel-Halim, Mohammad; Tinsley, Heather; Keeton, Adam B.; Weam, Mohammed; Atta, Noha H.; Hammam, Mennatallah A.; Hefnawy, Amr; Hartmann, Rolf W.; Engel, Matthias; Piazza, Gary A.; Abadi, Ashraf H. | |
| article | 2019 | 2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 1. Identification of an Allosteric Binding Site | Bestgen, Benoît; Krimm, Isabelle; Kufareva, Irina; Kamal, Ahmed Ashraf Moustafa; Seetoh, Wei-Guang; Abell, Chris; Hartmann, Rolf W.; Abagyan, Ruben; Cochet, Claude; Le Borgne, Marc; Engel, Matthias; Lomberget, Thierry | |
| article | 2019 | 2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 2. Structure-Based Optimization and Investigation of Effects Specific to the Allosteric Mode of Action | Bestgen, Benoît; Kufareva, Irina; Seetoh, Weiguang; Abell, Chris; Hartmann, Rolf W.; Abagyan, Ruben; Le Borgne, Marc; Filhol, Odile; Cochet, Claude; Lomberget, Thierry; Engel, Matthias | |
| article | 2018 | Development of novel amide-derivatized 2,4-bispyridyl thiophenes as highly potent and selective Dyrk1A inhibitors. Part II : Identification of the cyclopropylamide moiety as a key modification | Darwish, Sarah S.; Abdel-Halim, Mohammad; ElHady, Ahmed K.; Salah, Mohamed; Abadi, Ashraf H.; Becker, Walter; Engel, Matthias | |
| article | 2018 | Development of novel 2,4-bispyridyl thiophene-based compounds as highly potent and selective Dyrk1A inhibitors. Part I : Benzamide and benzylamide derivatives | Darwish, Sarah S.; Abdel-Halim, Mohammad; Salah, Mohamed; Abadi, Ashraf H.; Becker, Walter; Engel, Matthias | |
https://orcid.org/0000-0001-5065-8634