List of publications
Dokumenttyp | Erscheinungsjahr | Titel | Autoren | Herausgeber |
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article | 2023 | Physiologically based pharmacokinetic modeling of tacrolimus for food-drug and CYP3A drug-drug-gene interaction predictions | Loer, Helena Leonie Hanae; Feick, Denise; Rüdesheim, Simeon; Selzer, Dominik; Schwab, Matthias; Teutonico, Donato; Frechen, Sebastian; van der Lee, Maaike; Moes, Dirk Jan A. R.; Swen, Jesse J.; Lehr, Thorsten | |
article | 2023 | Physiologically-based pharmacokinetic modeling of quinidine to establish a CYP3A4, P-gp, and CYP2D6 drug-drug-gene interaction network | Feick, Denise; Rüdesheim, Simeon; Marok, Fatima Zahra; Selzer, Dominik; Loer, Helena Leonie Hanae; Teutonico, Donato; Frechen, Sebastian; van der Lee, Maaike; Moes, Dirk Jan A. R.; Swen, Jesse J.; Schwab, Matthias; Lehr, Thorsten | |
article | 2022 | Physiologically Based Pharmacokinetic (PBPK) Modeling of Clopidogrel and Its Four Relevant Metabolites for CYP2B6, CYP2C8, CYP2C19, and CYP3A4 Drug–Drug–Gene Interaction Predictions | Loer, Helena Leonie Hanae; Türk, Denise; Gómez-Mantilla, José David; Selzer, Dominik; Lehr, Thorsten | |
article | 2022 | Renal Transporter-Mediated Drug-Biomarker Interactions of the Endogenous Substrates Creatinine and N1 -Methylnicotinamide : A PBPK Modeling Approach | Türk, Denise; Müller, Fabian; Fromm, Martin F.; Selzer, Dominik; Dallmann, Robert; Lehr, Thorsten | |
doctoralThesis | 2022 | Impact of drug-gene-disease interactions and diurnal variation on exogenous and endogenous renal transporter substrates : a physiologically based pharmacokinetic modeling approach | Feick, Denise | |