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Titel: Dental and oral health assessments in the German National Cohort (NAKO)
VerfasserIn: Samietz, Stefanie
Borof, Katrin
Hertrampf, Katrin
Aarabi, Ghazal
Ciardo, Antonio
Finke, Hannah
Hagenfeld, Daniel
Kühnisch, Jan
Rütters, Maurice
Baumeister, Sebastian-Edgar
Reckelkamm, Stefan Lars
Kim, Ti-Sun
Kocher, Thomas
Ahrens, Wolfgang
Brenner, Hermann
Emmel, Carina
Fischer, Beate
Führer, Amand
Greiser, Karin Halina
Grischke, Jasmin
Günther, Kathrin
Harth, Volker
Jaskulski, Stefanie
Karch, André
Keil, Thomas
Kemmling, Yvonne
Kluttig, Alexander
Krist, Lilian
Kuss, Oliver
Leitzmann, Michael
Meinke-Franze, Claudia
Michels, Karin B.
Obi, Nadia
Peters, Anette
Pischon, Nicole
Pischon, Tobias
Schipf, Sabine
Schmidt, Börge
Teismann, Henning
Rupf, Stefan
Holtfreter, Birte
Sprache: Englisch
Titel: BMC Oral Health
Bandnummer: 25
Heft: 1
Verlag/Plattform: BMC
Erscheinungsjahr: 2025
Freie Schlagwörter: Epidemiology
Cohort study
Cross-sectional
Caries
Periodontitis
Dental status
Temporomandibular disorders
Oral health
DDC-Sachgruppe: 610 Medizin, Gesundheit
Dokumenttyp: Journalartikel / Zeitschriftenartikel
Abstract: Background Despite considerable improvements in oral health in recent decades, caries and periodontitis are still widespread, ranking among the most prevalent diseases worldwide and requiring future research. The German National Cohort (NAKO Gesundheitsstudie, NAKO) is a large-scaled, multidisciplinary, nationwide, multi-centre, pop‑ ulation-based, prospective cohort study with oral examinations that aims to provide a resource to study risk factors for major diseases. The aim of the present article is to provide the methodological background, to report on the data quality, and to present initial results of the oral examinations. Methods During baseline examinations (2014–2019), a total of 205,184 persons aged 19–74 years has been examined in 18 study centres, including, among others, a dental interview, stimulated saliva sampling, and record‑ ing of the numbers of present teeth and prostheses (standard Level 1 program). As part of the Level 2 program that was ofered to 20% randomly selected participants, each study centre selected one of three modules, one of them being the Level 2 oral examination. This extended program was carried out in a subgroup of 20,828 par‑ ticipants, including collection of detailed information on the dental and prosthetic status as well as on periodontal, cariological and functional aspects. To ensure reliability and reproducibility, study nurses were trained and calibrated by dental experts. In addition, a reliability study was conducted among 794 Level 1 and 359 Level 2 participants, reporting intra class correlation and kappa coefcients. Results Intra class correlation and kappa coefcients for observer agreement and reliability were consistently above 0.7, indicating good to excellent reliability of all dental measurements. For example, intra class correlation was 0.937 for the number of present teeth (Level 1), 0.740 for mean probing depth (PD) and 0.797 for active mouth opening. An initial inspection of the data showed that the median number of present teeth was 27, of which on average 6.9 teeth were healthy and caries-free. Average mean PD was 1.92 mm. An orthodontic treatment was reported by 35.5% of participants. Discussion Overall, the dental study protocol was feasible and successfully integrated into the NAKO’s overall assess‑ ment program. However, rigorous support of the study centres by dental professionals was required to ensure high quality data. In summary, high-quality data collection within the NAKO pave the way for future investigation of poten‑ tial risk factors for oral diseases and links between oral and systemic diseases and conditions.
DOI der Erstveröffentlichung: 10.1186/s12903-025-05454-z
URL der Erstveröffentlichung: https://bmcoralhealth.biomedcentral.com/articles/10.1186/s12903-025-05454-z
Link zu diesem Datensatz: urn:nbn:de:bsz:291--ds-444059
hdl:20.500.11880/39670
http://dx.doi.org/10.22028/D291-44405
ISSN: 1472-6831
Datum des Eintrags: 17-Feb-2025
Bezeichnung des in Beziehung stehenden Objekts: Supplementary Information
In Beziehung stehendes Objekt: https://static-content.springer.com/esm/art%3A10.1186%2Fs12903-025-05454-z/MediaObjects/12903_2025_5454_MOESM1_ESM.docx
Fakultät: M - Medizinische Fakultät
Fachrichtung: M - Zahn-, Mund- und Kieferheilkunde
Professur: M - Prof. Dr. med. dent. Stefan Rupf
Sammlung:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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