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Titel: Endovascular thrombectomy: an effective and safe therapy for perioperative ischemic stroke
VerfasserIn: Wang, Feng
Xu, Xiaoping
Zheng, Lin
Zhong, Jiawei
Wang, En
Liu, Yang
Ke, Shaofa
Sprache: Englisch
Titel: Frontiers in Neurology
Bandnummer: 15
Verlag/Plattform: Frontiers
Erscheinungsjahr: 2024
Freie Schlagwörter: perioperative stroke
community-onset stroke
endovascular thrombectomy
intracranial hemorrhage
prognosis
DDC-Sachgruppe: 610 Medizin, Gesundheit
Dokumenttyp: Journalartikel / Zeitschriftenartikel
Abstract: Background: Perioperative ischemic stroke is a rare but devastating complication. Mechanical thrombectomy is a promising therapeutic method, but very little data is available on its efficacy and safety. This study aims to answer this question by comparing the clinical outcomes of perioperative and community-onset stroke patients after endovascular therapy. Methods: A retrospective cohort study was conducted on a total of 35 perioperative and 584 community-onset acute ischemic stroke patients who underwent endovascular thrombectomy at our hospital over the past 3.5  years. The recanalization rate, clinical recovery and cerebral hemorrhage within 90  days after therapy were compared between these two patient groups. Results: Endovascular thrombectomy provided perioperative and communityonset ischemic stroke patients with comparable rates of successful reperfusion (mTICI ≥2b grade) (97.1% vs. 97.3%; p  =  0. 967) and favorable functional recovery (mRS ≤  2) (51.4% vs. 43.3%, p  =  0.348), with no increase in severe intracranial hemorrhage (0% vs. 2.6 and 1.0%, for hematoma ≥30% of infarcted tissue and intraventricular hemorrhage, respectively) within 90  days. In addition, perioperative stroke patients had higher prevalence of atrial fibrillation (42.9% vs. 26.7%; p  =  0.038) and intracranial cerebral artery stenosis without clear embolism (17.1% vs. 3.8%; p  <  0.001) than community-onset stroke patients. Conclusion: Endovascular thrombectomy is an effective and safe therapeutic approach for patients with perioperative ischemic stroke, although the results need to be validated by further studies with larger populations. Atrial fibrillation and large artery stenosis may contribute to the pathogenesis of perioperative ischemic stroke.
DOI der Erstveröffentlichung: 10.3389/fneur.2024.1489296
URL der Erstveröffentlichung: https://doi.org/10.3389/fneur.2024.1489296
Link zu diesem Datensatz: urn:nbn:de:bsz:291--ds-443560
hdl:20.500.11880/39630
http://dx.doi.org/10.22028/D291-44356
ISSN: 1664-2295
Datum des Eintrags: 12-Feb-2025
Bezeichnung des in Beziehung stehenden Objekts: Supplementary Material
In Beziehung stehendes Objekt: https://www.frontiersin.org/api/v3/articles/1489296/file/Table_1.docx/1489296_table_1/2
https://www.frontiersin.org/api/v3/articles/1489296/file/Table_2.docx/1489296_table_2/2
Fakultät: M - Medizinische Fakultät
Fachrichtung: M - Neurologie und Psychiatrie
Professur: M - Prof. Dr. Klaus Faßbender
Sammlung:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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