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doi:10.22028/D291-43633
Titel: | Exosomes and their derivatives as biomarkers and therapeutic delivery agents for cardiovascular diseases: Situations and challenges |
VerfasserIn: | Xu, Yunyang Wan, Weimin Zeng, Huixuan Xiang, Ze Li, Mo Yiwen, Yao Li, Yuan Bortolanza, Mariza Wu, Jian |
Sprache: | Englisch |
Titel: | Journal of translational internal medicine : TJIM |
Bandnummer: | 11 |
Heft: | 4 |
Verlag/Plattform: | De Gruyter |
Erscheinungsjahr: | 2023 |
Freie Schlagwörter: | cardiovascular disease exosome miRNA diagnosis prognosis Introduction |
DDC-Sachgruppe: | 610 Medizin, Gesundheit |
Dokumenttyp: | Journalartikel / Zeitschriftenartikel |
Abstract: | Microvesicles known as exosomes have a diameter of 40 to 160 nm and are derived from small endosomal membranes. Exosomes have attracted increasing attention over the past ten years in part because they are functional vehicles that can deliver a variety of lipids, proteins, and nucleic acids to the target cells they encounter. Because of this function, exosomes may be used for the diagnosis, prognosis and treatment of many diseases. All throughout the world, cardiovascular diseases (CVDs) continue to be a significant cause of death. Because exosomes are mediators of communication between cells, which contribute to many physiological and pathological aspects, they may aid in improving CVD therapies as biomarkers for diagnosing and predicting CVDs. Many studies demonstrated that exosomes are associated with CVDs, such as coronary artery disease, heart failure, cardiomyopathy and atrial fibrillation. Exosomes participate in the progression or inhibition of these diseases mainly through the contents they deliver. However, the application of exosomes in diferent CVDs is not very mature. So further research is needed in this field. |
DOI der Erstveröffentlichung: | 10.2478/jtim-2023-0124 |
URL der Erstveröffentlichung: | https://www.degruyter.com/document/doi/10.2478/jtim-2023-0124/html |
Link zu diesem Datensatz: | urn:nbn:de:bsz:291--ds-436333 hdl:20.500.11880/39098 http://dx.doi.org/10.22028/D291-43633 |
ISSN: | 2224-4018 2450-131X |
Datum des Eintrags: | 3-Dez-2024 |
Fakultät: | M - Medizinische Fakultät |
Fachrichtung: | M - Innere Medizin |
Professur: | M - Prof. Dr. Robert Bals |
Sammlung: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
Dateien zu diesem Datensatz:
Datei | Beschreibung | Größe | Format | |
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10.2478_jtim-2023-0124.pdf | 860,48 kB | Adobe PDF | Öffnen/Anzeigen |
Diese Ressource wurde unter folgender Copyright-Bestimmung veröffentlicht: Lizenz von Creative Commons