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Titel: Exosomes and their derivatives as biomarkers and therapeutic delivery agents for cardiovascular diseases: Situations and challenges
VerfasserIn: Xu, Yunyang
Wan, Weimin
Zeng, Huixuan
Xiang, Ze
Li, Mo
Yiwen, Yao
Li, Yuan
Bortolanza, Mariza
Wu, Jian
Sprache: Englisch
Titel: Journal of translational internal medicine : TJIM
Bandnummer: 11
Heft: 4
Verlag/Plattform: De Gruyter
Erscheinungsjahr: 2023
Freie Schlagwörter: cardiovascular disease
exosome
miRNA
diagnosis
prognosis Introduction
DDC-Sachgruppe: 610 Medizin, Gesundheit
Dokumenttyp: Journalartikel / Zeitschriftenartikel
Abstract: Microvesicles known as exosomes have a diameter of 40 to 160 nm and are derived from small endosomal membranes. Exosomes have attracted increasing attention over the past ten years in part because they are functional vehicles that can deliver a variety of lipids, proteins, and nucleic acids to the target cells they encounter. Because of this function, exosomes may be used for the diagnosis, prognosis and treatment of many diseases. All throughout the world, cardiovascular diseases (CVDs) continue to be a significant cause of death. Because exosomes are mediators of communication between cells, which contribute to many physiological and pathological aspects, they may aid in improving CVD therapies as biomarkers for diagnosing and predicting CVDs. Many studies demonstrated that exosomes are associated with CVDs, such as coronary artery disease, heart failure, cardiomyopathy and atrial fibrillation. Exosomes participate in the progression or inhibition of these diseases mainly through the contents they deliver. However, the application of exosomes in diferent CVDs is not very mature. So further research is needed in this field.
DOI der Erstveröffentlichung: 10.2478/jtim-2023-0124
URL der Erstveröffentlichung: https://www.degruyter.com/document/doi/10.2478/jtim-2023-0124/html
Link zu diesem Datensatz: urn:nbn:de:bsz:291--ds-436333
hdl:20.500.11880/39098
http://dx.doi.org/10.22028/D291-43633
ISSN: 2224-4018
2450-131X
Datum des Eintrags: 3-Dez-2024
Fakultät: M - Medizinische Fakultät
Fachrichtung: M - Innere Medizin
Professur: M - Prof. Dr. Robert Bals
Sammlung:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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