Bitte benutzen Sie diese Referenz, um auf diese Ressource zu verweisen: doi:10.22028/D291-41626
Volltext verfügbar? / Dokumentlieferung
Titel: Active perinatal care of preterm infants in the German Neonatal Network
VerfasserIn: Humberg, Alexander
Härtel, Christoph
Rausch, Tanja K.
Stichtenoth, Guido
Jung, Philipp
Wieg, Christian
Kribs, Angela
von der Wense, Axel
Weller, Ursula
Höhn, Thomas
Olbertz, Dirk M.
Felderhoff-Müser, Ursula
Rossi, Rainer
Teig, Norbert
Heitmann, Friedhelm
Schmidtke, Susanne
Bohnhorst, Bettina
Vochem, Matthias
Segerer, Hugo
Möller, Jens
Eichhorn, Joachim G.
Wintgens, Jürgen
Böttger, Ralf
Hubert, Mechthild
Dördelmann, Michael
Hillebrand, Georg
Roll, Claudia
Jensen, Reinhard
Zemlin, Michael
Mögel, Michael
Werner, Claudius
Schäfer, Stefan
Schaible, Thomas
Franz, Axel
Heldmann, Michael
Ehlers, Silke
Kannt, Olaf
Orlikowsky, Thorsten
Gerleve, Hubert
Schneider, Katja
Haase, Roland
Böckenholt, Kai
Linnemann, Knud
Herting, Egbert
Göpel, Wolfgang
Sprache: Englisch
Titel: Archives of Disease in Childhood. Fetal and Neonatal Edition
Bandnummer: 105 (2020)
Heft: 2
Seiten: F190-F195
Verlag/Plattform: BMJ
Erscheinungsjahr: 2019
DDC-Sachgruppe: 610 Medizin, Gesundheit
Dokumenttyp: Journalartikel / Zeitschriftenartikel
Abstract: Objective To determine if survival rates of preterm infants receiving active perinatal care improve over time. Design The German Neonatal Network is a cohort study of preterm infants with birth weight <1500 g. All eligible infants receiving active perinatal care are registered. We analysed data of patients discharged between 2011 and 2016. Setting 43 German level III neonatal intensive care units (NICUs). Patients 8222 preterm infants with a gestational age between 22/0 and 28/6 weeks who received active perinatal care. Interventions Participating NICUs were grouped according to their specific survival rate from 2011 to 2013 to high (percentile >P75), intermediate (P25–P75) and low (<P25) survival. We compared these survival rates with data in 2014–2016. Main outcome measures Death by any cause before discharge. Results Total survival increased from 85.8% in 2011–2013 to 87.4% in 2014–2016. This increase was due to reduced mortality of NICUs with low survival rates in 2011–2013. Survival increased in these centres from 53% to 64% in the 22–24 weeks strata and from 73% to 84% in the 25–26 weeks strata. Conclusions Our data support previous reports that active perinatal care of very immature infants improves outcomes at the border of viability and survival rates at higher gestational ages. The high total number of surviving infants below 24 weeks of gestation challenges national recommendations exclusively referring to gestational age as the single criterion for providing active care. However, more data are needed before recommendations for parental counselling should be reconsidered. Trial registration Approval by the local institutional review board for research in human subjects of the University of Lübeck (file number 08–022) and by the local ethic committees of all participating centres has been given.
DOI der Erstveröffentlichung: 10.1136/archdischild-2018-316770
URL der Erstveröffentlichung: https://doi.org/10.1136/archdischild-2018-316770
Link zu diesem Datensatz: urn:nbn:de:bsz:291--ds-416269
hdl:20.500.11880/37280
http://dx.doi.org/10.22028/D291-41626
ISSN: 1468-2052
1359-2998
Datum des Eintrags: 13-Feb-2024
Fakultät: M - Medizinische Fakultät
Fachrichtung: M - Pädiatrie
Professur: M - Prof. Dr. Michael Zemlin
Sammlung:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

Dateien zu diesem Datensatz:
Es gibt keine Dateien zu dieser Ressource.


Alle Ressourcen in diesem Repository sind urheberrechtlich geschützt.