Please use this identifier to cite or link to this item: doi:10.22028/D291-41131
Title: Reliability analysis of successive Corneal Visualization Scheimpflug Technology measurements in different keratoconus stages
Author(s): Flockerzi, Elias
Häfner, Larissa
Xanthopoulou, Kassandra
Daas, Loay
Munteanu, Cristian
Langenbucher, Achim
Seitz, Berthold
Language: English
Title: Acta Ophthalmologica
Volume: 100 (2022)
Issue: 1
Pages: e83-e90
Publisher/Platform: Wiley
Year of Publication: 2021
Free key words: cornea
corvis ST
dynamic corneal response
DDC notations: 610 Medicine and health
Publikation type: Journal Article
Abstract: ABSTRACT. Background: This study assesses the reliability of successive corneal biomechanical response measurements by the Corneal Visualization Scheimpflug Technology (CST, Corvis ST , Oculus Optikger€ate, Wetzlar, Germany) in different keratoconus (KC) stages. Methods: A total of 173 eyes (15 controls: 15 eyes, and 112 KC patients: stages 1|1–2|2|2–3|3|3–4|4, n = 26|16|36|18|31|26|5 according to Topographical KC Classification, TKC) were repeatedly examined five times with the CST, each after repositioning the patient’s head and re-adjusting the device. Tomographical analysis (Pentacam HR ; Oculus, Wetzlar, Germany) was performed once before and once after CST measurements. Outcome measures included (1) A1 velocity, (2) deformation amplitude (DA) ratio 2 mm, (3) integrated radius, (4) stiffness parameter A1 and (5) Ambrosio relational thickness to the horizontal profile (ARTh). The Corvis Biomechanical Index (CBI) is reported to be extracted out of these parameters. Mean values of the five measurements and Cronbach’s a were calculated as a measure for reliability. Results: Ambrosio relational thickness to the horizontal profile and SPA1 were significantly higher in controls (534|123) compared to TKC1 (384|88), TKC2 (232|66), TKC3 (152|55) and TKC4 (71|27; p < 0.0001). The other parameters were similar in controls and TKC1 (A1 velocity: 0.148|0.151 m/s; integrated radius: 8.2|8.6 mm 1 ), but significantly higher in TKC stages 2 to 4 (DA ratio 2 mm: 5.5|6.3|8.0; A1 velocity: 0.173|0.174|0.186 m/second; integrated radius: 10.9|12.8|19.0 mm 1 ; p < 0.0001). All parameters proved to be highly reliable (Cronbach’s a ≥ 0.834) and the corneal tomography remained unaffected. Conclusions: The individual parameters included in the CBI (consisting of ARTh, SPA1, DA ratio 2 mm, A1 velocity and integrated radius) are highly reliable but differ KC stage-dependently.
DOI of the first publication: 10.1111/aos.14857
URL of the first publication:
Link to this record: urn:nbn:de:bsz:291--ds-411313
ISSN: 1755-3768
Date of registration: 21-Nov-2023
Faculty: M - Medizinische Fakultät
Department: M - Augenheilkunde
Professorship: M - Univ.-Prof. Dr. Dipl.-Ing. Achim Langenbucher
M - Prof. Dr. Berthold Seitz
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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