Please use this identifier to cite or link to this item: doi:10.22028/D291-41112
Title: Sensing and avoiding sick conspecifics requires Gαi2+ vomeronasal neurons
Author(s): Weiss, Jan
Vacher, Hélène
Trouillet, Anne-Charlotte
Leinders-Zufall, Trese
Zufall, Frank
Chamero, Pablo
Language: English
Title: BMC Biology
Volume: 21
Publisher/Platform: BMC
Year of Publication: 2023
Free key words: LPS
Vomeronasal organ
Ca2+ imaging
Dendritic knob
Avoidance behavior
Lateral habenula
DDC notations: 570 Life sciences, biology
Publikation type: Journal Article
Abstract: Rodents utilize chemical cues to recognize and avoid other conspecifics infected with pathogens. Infection with pathogens and acute inflammation alter the repertoire and signature of olfactory stimuli emitted by a sick individual. These cues are recognized by healthy conspecifics via the vomeronasal or accessory olfactory system, triggering an innate form of avoidance behavior. However, the molecular identity of the sensory neurons and the higher neural circuits involved in the detection of sick conspecifics remain poorly understood.
DOI of the first publication: 10.1186/s12915-023-01653-8
URL of the first publication:
Link to this record: urn:nbn:de:bsz:291--ds-411123
ISSN: 1741-7007
Date of registration: 20-Nov-2023
Faculty: M - Medizinische Fakultät
Department: M - Physiologie
Professorship: M - Prof. Dr. Trese Leinders-Zufall
M - Prof. Dr. Frank Zufall
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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