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Titel: Birth weight, Apgar scores and gentamicin were associated with acute kidney injuries in VLBW neonates requiring treatment for patent ductus arteriosus
VerfasserIn: Aygün, Aylin
Poryo, Martin
Wagenpfeil, Gudrun
Wissing, Antonia
Ebrahimi-Fakhari, Daniel
Zemlin, Michael
Gortner, Ludwig
Meyer, Sascha
Sprache: Englisch
Titel: Acta Paediatrica : Nurturing the Child
Bandnummer: 108
Heft: 4
Seiten: 645–653
Verlag/Plattform: Wiley
Erscheinungsjahr: 2019
Freie Schlagwörter: Acute kidney injury
Ibuprofen
Patent ductus arteriosus
Surgery
Very low birth weight infants
DDC-Sachgruppe: 610 Medizin, Gesundheit
Dokumenttyp: Journalartikel / Zeitschriftenartikel
Abstract: We assessed the risk factors for transient acute kidney injury in very low birth weight (VLBW) infants treated for patent ductus arteriosus (PDA) using the serum creatininebased criteria in Kidney Disease: Improving Global Outcomes. This retrospective study of infants requiring ibuprofen and, or, surgery for haemodynamic relevant PDAs was performed at the University Children’s Hospital of Saarland, Homburg, Germany, from January 2009 to December 2015. We studied 422 infants with a mean birth weight of 1059 308.2 g. Acute kidney injuries developed in 150/295 infants (50.9%) with spontaneous PDA closure, in 46/82 (56.1%) who received intravenous ibuprofen treatment, in 18/24 (75.0%) who had surgery and in 15/21 infants (71.4%) who received both medical and surgical treatment. Acute kidney injuries were associated with birth weight and gestational age, Apgar scores at 10 minutes, the PDA size corrected for birth weight, a PDA with three affected circulatory territories, PDA surgery and gentamicin. Multiple logistic regression analysis showed particular associations between acute kidney injury and birth weight (p = 0.001), the 10-minute Apgar score (p = 0.02) and gentamicin (p = 0.043). Birth weight, the 10-minute Apgar score and gentamicin were particularly associated with acute kidney injuries in our cohort.
DOI der Erstveröffentlichung: 10.1111/apa.14563
URL der Erstveröffentlichung: https://onlinelibrary.wiley.com/doi/pdf/10.1111/apa.14563
Link zu diesem Datensatz: urn:nbn:de:bsz:291--ds-403978
hdl:20.500.11880/36318
http://dx.doi.org/10.22028/D291-40397
ISSN: 0803-5253
Datum des Eintrags: 28-Aug-2023
Fakultät: M - Medizinische Fakultät
Fachrichtung: M - Medizinische Biometrie, Epidemiologie und medizinische Informatik
M - Pädiatrie
Professur: M - Prof. Dr. Michael Zemlin
M - Keiner Professur zugeordnet
Sammlung:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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