Please use this identifier to cite or link to this item: doi:10.22028/D291-39853
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Title: Accuracy of optical coherence tomography imaging in assessing aneurysmal remnants after flow diversion
Author(s): Fries, Frederik
Maßmann, Alexander
Tomori, Toshiki
Yilmaz, Umut
Kettner, Michael
Simgen, Andreas
Cattaneo, Giorgio
Wagenpfeil, Gudrun
Reith, Wolfgang
Mühl-Benninghaus, Ruben
Language: English
Title: Journal of neurointerventional surgery
Volume: 12
Issue: 12
Pages: 1242-1246
Publisher/Platform: BMJ
Year of Publication: 2020
Free key words: aneurysm
flow diverter
DDC notations: 610 Medicine and health
Publikation type: Journal Article
Abstract: Background: Optical coherence tomography (OCT) is an ultra-high resolution real-time intravascular imaging method that is gaining interest in cerebrovascular applications. Objective: To compare, in a rabbit elastase aneurysm model, digital subtraction angiography (DSA) and OCT as diagnostic tools for the assessment of aneurysmal remnants and baseline characteristics of aneurysms after flow diverter (FD) implantation. Methods: With Institutional Animal Care and Use Committee approval, saccular aneurysms were created in 28 rabbits and treated with Derivo FDs. DSA was performed before, and immediately after, stent implantation. As a follow-up, DSA and OCT were performed 28 days after device implantation. Results: DSA and OCT were successfully performed in 23 cases. OCT could not be achieved in 5 cases owing to navigational difficulties in the stent lumen with the OCT catheter. Residual aneurysms were significantly more often visible with OCT (18/23 (78%) than with DSA 12/23 (52%), p = 0.031). Conclusion: OCT was more sensitive than conventional angiography for the assessment of residual aneurysms at 28 days after FD implantation in an animal model.
DOI of the first publication: 10.1136/neurintsurg-2020-016129
URL of the first publication:
Link to this record: urn:nbn:de:bsz:291--ds-398535
ISSN: 1759-8478
Date of registration: 26-May-2023
Faculty: M - Medizinische Fakultät
Department: M - Radiologie
Professorship: M - Prof. Dr. Wolfgang Reith
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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