Please use this identifier to cite or link to this item: doi:10.22028/D291-39818
Title: Associations between long-term exercise participation and lower limb joint and whole-bone geometry in young and older adults
Author(s): Scorcelletti, Matteo
Zange, Jochen
Böcker, Jonas
Sies, Wolfram
Lau, Patrick
Mittag, Uwe
Reeves, Neil D.
Ireland, Alex
Rittweger, Jörn
Language: English
Title: Frontiers in Physiology
Volume: 14
Publisher/Platform: Frontiers
Year of Publication: 2023
Free key words: femur shape
hip shape
master athletes
skeletal development
DDC notations: 610 Medicine and health
Publikation type: Journal Article
Abstract: Introduction: Features of lower limb bone geometry are associated with movement kinematics and clinical outcomes including fractures and osteoarthritis. Therefore, it is important to identify their determinants. Lower limb geometry changes dramatically during development, partly due to adaptation to the forces experienced during physical activity. However, the effects of adulthood physical activity on lower limb geometry, and subsequent associations with muscle function are relatively unexplored. Methods: 43 adult males were recruited; 10 young (20–35 years) trained i.e., regional to world-class athletes, 12 young sedentary, 10 older (60–75 years) trained and 11 older sedentary. Skeletal hip and lower limb geometry including acetabular coverage and version angle, total and regional femoral torsion, femoral and tibial lateral and frontal bowing, and frontal plane lower limb alignment were assessed using magnetic resonance imaging. Muscle function was assessed recording peak power and force of jumping and hopping using mechanography. Associations between age, training status and geometry were assessed using multiple linear regression, whilst associations between geometry and muscle function were assessed by linear mixed effects models with adjustment for age and training. Results: Trained individuals had 2° (95% CI:0.6°–3.8°; p = 0.009) higher femoral frontal bowing and older individuals had 2.2° (95% CI:0.8°–3.7°; p = 0.005) greater lateral bowing. An age-by-training interaction indicated 4° (95% CI:1.4°–7.1°; p = 0.005) greater acetabular version angle in younger trained individuals only. Lower limb geometry was not associated with muscle function (p > 0.05). Discussion: The ability to alter skeletal geometry via exercise in adulthood appears limited, especially in epiphyseal regions. Furthermore, lower limb geometry does not appear to be associated with muscle function.
DOI of the first publication: 10.3389/fphys.2023.1150562
URL of the first publication:
Link to this record: urn:nbn:de:bsz:291--ds-398183
ISSN: 1664-042X
Date of registration: 23-May-2023
Description of the related object: Supplementary Material
Related object:
Faculty: M - Medizinische Fakultät
Department: M - Chirurgie
Professorship: M - Prof. Dr. med. Bergita Ganse
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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