Please use this identifier to cite or link to this item: doi:10.22028/D291-39811
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Title: Effects of a Feedback-Demanding Stroke Clock on Acute Stroke Management: A Randomized Study
Author(s): Fousse, Mathias
Grün, Daniel
Helwig, Stefan A
Walter, Silke
Bekhit, Adam
Wagenpfeil, Stefan
Lesmeister, Martin
Kettner, Michael
Roumia, Safwan
Mühl-Benninghaus, Ruben
Simgen, Andreas
Yilmaz, Umut
Ruckes, Christian
Kronfeld, Kai
Bachhuber, Monika
Grunwald, Iris Q
Bertsch, Thomas
Reith, Wolfgang
Faßbender, Klaus
Language: English
Title: Stroke
Volume: 51
Issue: 10
Pages: 2895-2900
Publisher/Platform: Lippincott Williams & Wilkins
Year of Publication: 2020
Free key words: acute management
DDC notations: 610 Medicine and health
Publikation type: Journal Article
Abstract: Background and Purpose: This randomized study aimed to evaluate whether the use of a stroke clock demanding active feedback from the stroke physician accelerates acute stroke management. Methods: For this randomized controlled study, a large-display alarm clock was installed in the computed tomography room, where admission, diagnostic work-up, and intravenous thrombolysis occurred. Alarms were set at the following target times after admission: (1) 15 minutes (neurological examination completed); (2) 25 minutes (computed tomography scanning and international normalized ratio determination by point-of-care laboratory completed); and (3) 30 minutes (intravenous thrombolysis started). The responsible stroke physician had to actively provide feedback by pressing a buzzer button. The alarm could be avoided by pressing the button before time out. Times to therapy decision (primary end point, defined as the end of all diagnostic work-up required for decision for or against recanalizing treatment), neurological examination, imaging, point-of-care laboratory, needle, and groin puncture were assessed by a neutral observer. Functional outcome (modified Rankin Scale) was assessed at day 90. Results: Of 107 participants, 51 stroke clock patients exhibited better stroke-management metrics than 56 control patients. Times from door to (1) end of all indicated diagnostic work-up (treatment decision time; 16.73 versus 26.00 minutes, P<0.001), (2) end of neurological examination (7.28 versus 10.00 minutes, P<0.001), (3) end of computed tomography (11.17 versus 14.00 minutes, P=0.002), (4) end of computed tomography angiography (14.00 versus 17.17 minutes, P=0.001), (5) end of point-of-care laboratory testing (12.14 versus 20.00 minutes, P<0.001), and (6) needle times (18.83 versus 47.00 minutes, P=0.016) were improved. In contrast, door-to-groin puncture times and functional outcomes at day 90 were not significantly different. Conclusions: This study showed that the use of a stroke clock demanding active feedback significantly improves acute stroke-management metrics and, thus, represents a potential low-cost strategy for streamlining time-sensitive stroke treatment.
DOI of the first publication: 10.1161/STROKEAHA.120.029222
URL of the first publication:
Link to this record: urn:nbn:de:bsz:291--ds-398113
ISSN: 0039-2499
Date of registration: 22-May-2023
Faculty: M - Medizinische Fakultät
Department: M - Medizinische Biometrie, Epidemiologie und medizinische Informatik
M - Radiologie
Professorship: M - Prof. Dr. Wolfgang Reith
M - Prof. Dr. Stefan Wagenpfeil
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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