Please use this identifier to cite or link to this item: doi:10.22028/D291-39785
Volltext verfügbar? / Dokumentlieferung
Title: Efficacy, safety, and predictability of transepithelial photorefractive keratectomy: meta-analysis
Author(s): Sabau, Alexandra
Daas, Loay
Behkit, Abdelshafi
Wagenpfeil, Stefan
Langenbucher, Achim
Ardjomand, Navid
Flockerzi, Elias
Seitz, Berthold
Language: English
Title: Journal of cataract and refractive surgery
Volume: 47
Issue: 5
Pages: 634-640
Publisher/Platform: Lippincott Williams & Wilkins
Year of Publication: 2021
DDC notations: 610 Medicine and health
Publikation type: Journal Article
Abstract: Purpose: To evaluate the efficacy, safety, and predictability of transepithelial photorefractive keratectomy (TransPRK) for correcting myopia, astigmatism, and hyperopia. Setting: Department of Ophthalmology, Saarland University Medical Center, Homburg/Saar, Germany. Design: Meta-analysis of retrospective or prospective studies. Methods: Relevant studies were collected from Medline and included when meeting the following predefined criteria: randomized controlled trials, at least 1 of the main outcome measures as efficacy, safety, or predictability, and 1 common TransPRK laser (Schwind Amaris). The parameters estimates and 95% CI were derived from random-effects meta-analysis to account for possible heterogeneity. Results: Because hyperopia studies did not meet the inclusion criteria, the results are centered on myopia and astigmatism. Sixteen studies with a total of 1924 treated eyes were included in the meta-analysis. The mean efficacy, safety, and predictability had a probability of 94% (CI, 0.86-0.97), 0% (CI, 0.00-0.03), and 89% (CI, 0.82-0.93), respectively. The mean correction index, difference vector, and index of success had a value of 1.01 (CI, 1.01-1.02), 0.20 (CI, 0.06-0.34), and 0.12 (CI, 0.07-0.18), respectively. Conclusions: This summary estimate showed that TransPRK was highly effective, safe, and predictable in correcting myopia and/or astigmatism.
DOI of the first publication: 10.1097/j.jcrs.0000000000000487
Link to this record: urn:nbn:de:bsz:291--ds-397853
ISSN: 0886-3350
Date of registration: 16-May-2023
Faculty: M - Medizinische Fakultät
Department: M - Augenheilkunde
M - Medizinische Biometrie, Epidemiologie und medizinische Informatik
Professorship: M - Prof. Dr. Berthold Seitz
M - Prof. Dr. Stefan Wagenpfeil
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

Files for this record:
There are no files associated with this item.

Items in SciDok are protected by copyright, with all rights reserved, unless otherwise indicated.