Please use this identifier to cite or link to this item: doi:10.22028/D291-39755
Title: High BMI and Surgical Time Are Significant Predictors of Lymphocele after Robot-Assisted Radical Prostatectomy
Author(s): Gloger, Simon
Wagner, Christian
Leyh-Bannurah, Sami-Ramzi
Siemer, Stefan
Arndt, Madeleine
Stolzenburg, Jens-Uwe
Franz, Toni
Ubrig, Burkhard
Language: English
Title: Cancers
Volume: 15
Issue: 9
Publisher/Platform: MDPI
Year of Publication: 2023
Free key words: robot-assisted radical prostatectomy
symptomatic lymphocele
risk factors
pelvic lymph node dissection
peritoneal flap
DDC notations: 610 Medicine and health
Publikation type: Journal Article
Abstract: Lymphoceles (LC) occur in up to 60% after robot-assisted radical prostatectomy (RARP) and pelvic lymphadenectomy (PLND). In 2–10%, they are symptomatic and may cause complications and require treatment. Data on risk factors for the formation of lymphoceles after RARP and PNLD remain sparse in the urologic literature and are inconclusive to date. The underlying data of this secondary analysis were obtained from the prospective multi-center RCT ProLy. We performed a multivariate analysis to focus on the potential risk factors that may influence lymphocele formation. Patients with LC had a statistically significant higher BMI (27.8 vs. 26.3 kg/m2 , p < 0.001; BMI ≥ 30 kg/m2 : 31 vs. 17%, p = 0.002) and their surgical time was longer (180 vs. 160 min, p = 0.001) In multivariate analysis, the study group (control vs. peritoneal flap, p = 0.003), BMI (metric, p = 0.028), and surgical time (continuous, p = 0.007) were independent predictors. Patients with symptomatic lymphocele presented with higher BMI (29 vs. 26.6 kg/m2 , p = 0.007; BMI ≥ 30 kg/m2 : 39 vs. 20%, p = 0.023) and experienced higher intraoperative blood loss (200 vs. 150 mL, p = 0.032). In multivariate analysis, BMI ≥ 30 kg/m2 vs. < 30 kg/m2 was an independent predictor for the formation of a symptomatic lymphocele (p = 0.02). High BMI and prolonged surgical time are general risk factors for the development of LC. Patients with a BMI ≥ 30 kg/m2 had a higher risk for symptomatic lymphoceles.
DOI of the first publication: 10.3390/cancers15092611
URL of the first publication:
Link to this record: urn:nbn:de:bsz:291--ds-397559
ISSN: 2072-6694
Date of registration: 16-May-2023
Faculty: M - Medizinische Fakultät
Department: M - Urologie und Kinderurologie
Professorship: M - Prof. Dr. Michael Stöckle
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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