Please use this identifier to cite or link to this item: doi:10.22028/D291-39631
Title: Effects of Cold Atmospheric Plasma Pre-Treatment of Titanium on the Biological Activity of Primary Human Gingival Fibroblasts
Author(s): Gund, Madline P.
Naim, Jusef
Lehmann, Antje
Hannig, Matthias
Linsenmann, Constanze
Schindler, Axel
Rupf, Stefan
Language: English
Title: Biomedicines
Volume: 11
Issue: 4
Publisher/Platform: MDPI
Year of Publication: 2023
Free key words: biological cell activity
cell attachment
cold atmospheric plasma
primary human gingival fibroblasts
DDC notations: 610 Medicine and health
Publikation type: Journal Article
Abstract: Cold atmospheric plasma treatment (CAP) enables the contactless modification of titanium. This study aimed to investigate the attachment of primary human gingival fibroblasts on titanium. Machined and microstructured titanium discs were exposed to cold atmospheric plasma, followed by the application of primary human gingival fibroblasts onto the disc. The fibroblast cultures were analyzed by fluorescence, scanning electron microscopy and cell-biological tests. The treated titanium displayed a more homogeneous and denser fibroblast coverage, while its biological behavior was not altered. This study demonstrated for the first time the beneficial effect of CAP treatment on the initial attachment of primary human gingival fibroblasts on titanium. The results support the application of CAP in the context of pre-implantation conditioning, as well as of peri-implant disease treatment.
DOI of the first publication: 10.3390/biomedicines11041185
URL of the first publication:
Link to this record: urn:nbn:de:bsz:291--ds-396314
ISSN: 2227-9059
Date of registration: 2-May-2023
Faculty: M - Medizinische Fakultät
Department: M - Zahn-, Mund- und Kieferheilkunde
Professorship: M - Prof. Dr. Matthias Hannig
M - Prof. Dr. med. dent. Stefan Rupf
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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