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doi:10.22028/D291-39406
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Datei | Beschreibung | Größe | Format | |
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nutrients-15-01450.pdf | 691,72 kB | Adobe PDF | Öffnen/Anzeigen |
Titel: | Prevalence and Relevance of Vitamin D Deficiency in Newly Diagnosed Breast Cancer Patients : A Pilot Study |
VerfasserIn: | Zemlin, Cosima Altmayer, Laura Stuhlert, Caroline Schleicher, Julia Theresa Wörmann, Carolin Lang, Marina Scherer, Laura-Sophie Thul, Ida Clara Spenner, Lisanne Sophie Simon, Jana Alisa Wind, Alina Kaiser, Elisabeth ![]() Weber, Regine ![]() Goedicke-Fritz, Sybelle Wagenpfeil, Gudrun Zemlin, Michael ![]() Solomayer, Erich-Franz Reichrath, Jörg ![]() Müller, Carolin ![]() |
Sprache: | Englisch |
In: | |
Titel: | Nutrients |
Bandnummer: | 15 |
Heft: | 6 |
Verlag/Plattform: | MDPI |
Erscheinungsjahr: | 2023 |
Freie Schlagwörter: | vitamin D prognostic factors breast cancer nutrition |
DDC-Sachgruppe: | 610 Medizin, Gesundheit |
Dokumenttyp: | Journalartikel / Zeitschriftenartikel |
Abstract: | (1) Background: Vitamin D plays an important role in many types of cancer. It was the aim of this study to analyze serum 25-hydroxyvitamin D (25(OH)D) levels in newly diagnosed breast cancer patients, and the association with prognostic and lifestyle factors. (2) Methods: 110 nonmetastatic breast cancer patients were included in the prospective observational “BEGYN” study at Saarland University Medical Center between September 2019 and January 2021. At the initiation visit, serum 25(OH)D levels were measured. Clinicopathological data on prognosis, nutrition, and lifestyle were extracted from data files and obtained using a questionnaire. (3) Results: Median serum 25(OH)D in breast cancer patients was 24 ng/mL (range 5–65 ng/mL), with 64.8% of patients being vitamin D deficient. 25(OH)D was higher among patients that reported the use of vitamin D supplements (43 ng/mL versus 22 ng/mL; p < 0.001), and in summer compared to other seasons (p = 0.03). Patients with moderate vitamin D deficiency were less likely to have triple negative breast cancer (p = 0.047). (4) Conclusions: Routinely measured vitamin D deficiency is common in breast cancer patients and needs to be detected and treated. However, our results do not support the hypothesis that vitamin D deficiency may be a main prognostic factor for breast cancer. |
DOI der Erstveröffentlichung: | 10.3390/nu15061450 |
URL der Erstveröffentlichung: | https://www.mdpi.com/2072-6643/15/6/1450 |
Link zu diesem Datensatz: | urn:nbn:de:bsz:291--ds-394068 hdl:20.500.11880/35530 http://dx.doi.org/10.22028/D291-39406 |
ISSN: | 2072-6643 |
Datum des Eintrags: | 29-Mär-2023 |
Fakultät: | M - Medizinische Fakultät |
Fachrichtung: | M - Dermatologie M - Frauenheilkunde M - Medizinische Biometrie, Epidemiologie und medizinische Informatik M - Pädiatrie |
Professur: | M - Prof. Dr. E.-F. Solomayer M - Prof. Dr. Thomas Vogt M - Prof. Dr. Stefan Wagenpfeil M - Prof. Dr. Michael Zemlin |
Sammlung: | SciDok - Der Wissenschaftsserver der Universität des Saarlandes |
Diese Ressource wurde unter folgender Copyright-Bestimmung veröffentlicht: Lizenz von Creative Commons