Please use this identifier to cite or link to this item: doi:10.22028/D291-38928
Title: A practical approach to the guideline-directed pharmacological treatment of heart failure with reduced ejection fraction
Author(s): Abdin, Amr
Bauersachs, Johann
Soltani, Samira
Eden, Matthias
Frey, Norbert
Böhm, Michael
Language: English
Title: ESC Heart Failure
Volume: 10 (2023)
Issue: 1
Pages: 24-31
Publisher/Platform: Wiley
Year of Publication: 2022
Free key words: Heart failure
DDC notations: 610 Medicine and health
Publikation type: Journal Article
Abstract: Over the last 15–20 years, remarkable developments of heart failure (HF) pharmacotherapies have been achieved. However, HF remains a global healthcare challenge with more than 64 million patients worldwide. Optimization of guideline-directed chronic HF medical therapy is highly recommended with every patient visit to improve outcomes in patients with HF with reduced ejection fraction. However, the majority of patients in real-world settings are treated with doses that are lower than those with proven efficacy in clinical trials, which might be due to concerns of adverse effects and inertia of physicians. Likewise, a significant proportion of patients still do not receive all drug classes that could improve their prognosis. The recent European Society of Cardiology guidelines do not provide detailed recommendations on how these drug classes should be implemented in the treatment of inpatients to allow for both safety and a high likelihood of efficacy. We therefore propose a practical approach algorithm to support physicians to treat HF patients in their daily practice.
DOI of the first publication: 10.1002/ehf2.14197
URL of the first publication:
Link to this record: urn:nbn:de:bsz:291--ds-389287
ISSN: 2055-5822
Date of registration: 6-Feb-2023
Faculty: M - Medizinische Fakultät
Department: M - Innere Medizin
Professorship: M - Prof. Dr. Michael Böhm
Collections:SciDok - Der Wissenschaftsserver der Universität des Saarlandes

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